On the night before Thanksgiving, Peter and Brian get drunk and eat the whole turkey, so they have to get a new one on Thanksgiving Day. With Peter gone, Chris tries to take over as the man of the house.
Based on Agatha Christie's And Then There Were None, this episode sees nearly the whole of Quahog including the Griffins, Joe and Tom Tucker all invited to a party in their honour in a mysterious house. After the host is murdered, the guests must band together to try to figure out who the killer is. Yet, as more murders take place and more clues are revealed, the guests must decide who to turn into the police by morning. This episode was confirmed by Macfarlane to be a canon episode, the characters killed off in this episode have been officially terminated from the ...
After Peter catches Lois' dad, Carter, having an affair, he is strong-armed into keeping a secret. But when Peter accidentally spills the beans, Lois' mom demands a divorce, and Peter is in charge of Carter's return to bachelorhood.
Peter and Joe team up to execute a series of painful and humiliating Halloween pranks on unsuspecting family, friends and neighbors. While Brian shows Stewie the ropes of trick-or-treating, Meg sets out to attend her first high school Halloween party with high hopes for the evening.
Feeling discouraged with the progress of his writing career, Brian decides to throw in the towel until Stewie becomes his manager and one of his books hits the bestseller list. But when the fame goes to his head, Brian gets a wake-up call from Bill Maher. Meanwhile, Lois decides that she and Peter need separate beds, a decision that leaves Peter looking for a new cuddle buddy.
After a public disturbance, Peter and Brian are forced to attend a 12-step meeting to help kick their drinking problems. Unable to recognize his issue, Peter gets a visit from Death, who gives him a glimpse of what life would be like with and without "Mr. Booze" in his bloodstream.
Chris and Meg think their parents have it easy, and Peter and Lois beg to differ, so in order to teach them a lesson, they all trade roles. Chris goes to work at the brewery while Meg runs the house. While things start off well, it's not long until the stress of running a household and being the sole breadwinner break down Chris and Meg.
When the local dry cleaner loses Peter's favorite white shirt, he goes ballistic. Meanwhile, Brian tries to score on a date with a new friend, Denise, but ends up striking out. Instead of calling it quits on love, he decides to enlist Quagmire's help, but things get nasty when they start to compete for the affections of each other's old flames, Cheryl Tiegs and Jillian.