Frank Detomello is a slovenly zoo keeper, and simple father to the only young and bright girl named Shane, who catches a cold right after he swallowed a germ-ridden egg! The inside of his body is known as the "City of Frank". An unlikely hero of a policeman white blood cell, by the name of Osmosis Jones, works as a member of Immunity cell. But with that germ-ridden egg comes a mortal danger: Osmosis discovers Frank has really contracted a villainous and black-hearted deadly virus known as Thrax who arrives and is plotting to ultimately overheat Frank's body, killing him from the inside out! Thrax is motivated by trying to become the nastiest new virus, attempting to kill each new victim faster than the previous. His grandiose plan for Frank is death in 48 hours, breaking previous medical records! Meanwhile the pill that Frank took, Drix arrives in the body and covers Frank's throat with ice to cover the irritation. Osmosis Jones becomes his newest partner. Now it's all up to only ... Written by
Anthony Pereyra <email@example.com>
Warner Bros. animation was in serious financial trouble during the film's production, and in 2000 it came down to two options, green-light another film by Director Brad Bird who made the critically acclaimed film The Iron Giant, or this film, Warner Execs choose this film over Bird's and upon learning this Bird got so mad at Warner Bros. that he took his film with him to Disney and Pixar animation to be made, that film would be the highly successful The Incredibles, whereas this film bombed at the box office, was critically panned, and ultimately killed Warner Bros. Feature Animation. See more »
When Frank is talking to his daughter by the monkey cage, his lunch box is lying on its side. In the next shot, the bag is standing up. See more »
You keep those ideas inside that mushy little head of yours, or you'll find yourself in our next nosebleed.
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The opening credits are shown on strands on amoeba. See more »
A Great Class of Hygienic and Human Body Functions
Frank (Bill Murray) is a widow without hygienic and bad alimentary habits. He eats food that felt on the floor without cleaning, he does not wash his hands before eating and he eats only junk food. His daughter keeps unsuccessfully trying to correct his behavior. One day, Frank eats a dirty egg and gets a disease. From this moment on, the human body functions are showed through very funny and educational cartoons. The hero, Osmosis Jones, is a white globule, with Chris Rock's voice. The great Farrely brothers again surprise me. This funny (and sometimes scatological movie) is a great class of hygienic and human body functions. Chris Rock and Laurence Fishburne give a great performance with their voices. Bill Murry has the role of a disgusting character. An excellent and very educational movie, indicated also (or specially) for children. My vote is nine.
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