Frank Detomello is a slovenly zoo keeper, and simple father to the only young and bright girl named Shane, who catches a cold right after he swallowed a germ-ridden egg! The inside of his body is known as the "City of Frank". An unlikely hero of a policeman white blood cell, by the name of Osmosis Jones, works as a member of Immunity cell. But with that germ-ridden egg comes a mortal danger: Osmosis discovers Frank has really contracted a villainous and black-hearted deadly virus known as Thrax who arrives and is plotting to ultimately overheat Frank's body, killing him from the inside out! Thrax is motivated by trying to become the nastiest new virus, attempting to kill each new victim faster than the previous. His grandiose plan for Frank is death in 48 hours, breaking previous medical records! Meanwhile the pill that Frank took, Drix arrives in the body and covers Frank's throat with ice to cover the irritation. Osmosis Jones becomes his newest partner. Now it's all up to only ... Written by
Anthony Pereyra <firstname.lastname@example.org>
In the bladder sequence, you can see one of the characters carrying Pikachu of the Pokémons as a pet. See more »
When Shane decides not to go to Buffalo with Frank, we see the ticker above his door showing the scores of various sports games. The item "Seattle: 5 Oakland: 4" scrolls onto the screen in two consecutive shots. See more »
La Muerte, man! Esta aqui! He's gonna kill us dead, hombre!
No, no. Talk English, man. We ain't on Telemundo here.
See more »
The Warner Brothers logo comes up looking like a germ-like substance with tentacles (with a blue tint) matching the "feel" of the movie, and is static instead of the modern 3D animated sequence. See more »
Groovejet (If This Ain't Love)
Written by Cristiano Spiller (as C. Spiller), Sophie Ellis-Bextor (as S. Ellis Bextor),
R. Davis, V. Montana, Jr. and R. Walker
Performed by Cristiano Spiller (as DJ Spiller) and Lead Vocals by Sophie Ellis-Bextor (as Sophie Ellis Bextor)
Courtesy of Atlantic Recording Corp.
By Arrangement with Warner Special Products, JT Company (Italy), Blanco y Negro Music (Spain),
Scorpio Music (France), EMI Records Ltd., Kontor Records (Germany) and F&G Management
Contains a sample from Carol Williams "Love is You"
Courtesy of Salsoul Records See more »
I thought this movie was very good. The people leaving bad reviews are being too critical. This movie was meant to be fun. The way the inside of the body is a city, the white blood cells are the police, fireman, etc., the lymph nodes were the police stations, veins were highways, the stomach was a bus station/airport type place, and the germs and bacteria were, of course, the criminals, and so on. This movie gives a very imaginative way the body works to fight infection, as if the body was a city of people just like in the real world. You may need to have some sort of knowledge about the body to get some of the puns and jokes, maybe not very young kids will get it, but they will like the animation...this movie is even good for adults. I give the movie 8/10...I thought it was a very entertaining movie!!!!!
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