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Osmosis Jones (2001)

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A policeman white blood cell, with the help of a cold pill, must stop a deadly virus from destroying the human they live in, Frank.


4,571 ( 23)
1 win & 7 nominations. See more awards »



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Cast overview, first billed only:
Osmosis Jones (voice)
Thrax (voice)
Drix (voice)
Leah (voice)
Tom Colonic (voice)
Kidney Rock (voice)
Kenny Olson ...
Kidney Rock (voice)
Jason Krause ...
Kidney Rock (voice)
Kidney Rock (voice)
Stefanie Eulinberg ...
Kidney Rock (voice)
Jimmie Bones ...
Kidney Rock (voice)
Uncle Kracker ...
Kidney Rock (voice)
Additional Character Voice (voice)
Additional Character Voice (voice)


Frank Detomello is a slovenly zoo keeper, and simple father to the only young and bright girl named Shane, who catches a cold right after he swallowed a germ-ridden egg! The inside of his body is known as the "City of Frank". An unlikely hero of a policeman white blood cell, by the name of Osmosis Jones, works as a member of Immunity cell. But with that germ-ridden egg comes a mortal danger: Osmosis discovers Frank has really contracted a villainous and black-hearted deadly virus known as Thrax who arrives and is plotting to ultimately overheat Frank's body, killing him from the inside out! Thrax is motivated by trying to become the nastiest new virus, attempting to kill each new victim faster than the previous. His grandiose plan for Frank is death in 48 hours, breaking previous medical records! Meanwhile the pill that Frank took, Drix arrives in the body and covers Frank's throat with ice to cover the irritation. Osmosis Jones becomes his newest partner. Now it's all up to only ... Written by Anthony Pereyra <hypersonic91@yahoo.com>

Plot Summary | Plot Synopsis


She's got a jones for Osmosis. Leah. One hot hormone. See more »

Motion Picture Rating (MPAA)

Rated PG for bodily humor | See all certifications »

Parents Guide:





Release Date:

10 August 2001 (USA)  »

Also Known As:

Agent Bílá krvinka  »

Filming Locations:

Box Office


$70,000,000 (estimated)

Opening Weekend:

$5,271,248 (USA) (10 August 2001)


$13,596,911 (USA) (5 October 2001)

Company Credits

Show detailed on  »

Technical Specs


Sound Mix:

| |



Aspect Ratio:

2.35 : 1
See  »

Did You Know?


Kidney Rock, the band playing at The Zit, is rapper Kid Rock and his back-up band, including rapper Joe C., who died shortly before the film's release. See more »


Osmosis mouths saying "What is that cherry stank?" but the dialogue isn't heard until a moment later as the camera is on Leah. See more »


Osmosis: You want Osmosis?
Drix: You've got Osmosis!
See more »

Crazy Credits

The Warner Brothers logo comes up looking like a germ-like substance with tentacles (with a blue tint) matching the "feel" of the movie, and is static instead of the modern 3D animated sequence. See more »


Spoofs Independence Day (1996) See more »


Cool, Daddy Cool
Written by Kid Rock (as Robert J. Ritchie), Bob Crewe and Frank Slay, Jr.
Produced by Kid Rock
Performed by Kid Rock featuring Joe C. (as Joe C)
Courtesy of Lava/Atlantic Records
See more »

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User Reviews

Very fun and imaginative
15 November 2001 | by (United States) – See all my reviews

I thought this movie was very good. The people leaving bad reviews are being too critical. This movie was meant to be fun. The way the inside of the body is a city, the white blood cells are the police, fireman, etc., the lymph nodes were the police stations, veins were highways, the stomach was a bus station/airport type place, and the germs and bacteria were, of course, the criminals, and so on. This movie gives a very imaginative way the body works to fight infection, as if the body was a city of people just like in the real world. You may need to have some sort of knowledge about the body to get some of the puns and jokes, maybe not very young kids will get it, but they will like the animation...this movie is even good for adults. I give the movie 8/10...I thought it was a very entertaining movie!!!!!

25 of 27 people found this review helpful.  Was this review helpful to you?

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