Frank Detomello is a slovenly zoo keeper, and simple father to the only young and bright girl named Shane, who catches a cold right after he swallowed a germ-ridden egg! The inside of his body is known as the "City of Frank". An unlikely hero of a policeman white blood cell, by the name of Osmosis Jones, works as a member of Immunity cell. But with that germ-ridden egg comes a mortal danger: Osmosis discovers Frank has really contracted a villainous and black-hearted deadly virus known as Thrax who arrives and is plotting to ultimately overheat Frank's body, killing him from the inside out! Thrax is motivated by trying to become the nastiest new virus, attempting to kill each new victim faster than the previous. His grandiose plan for Frank is death in 48 hours, breaking previous medical records! Meanwhile the pill that Frank took, Drix arrives in the body and covers Frank's throat with ice to cover the irritation. Osmosis Jones becomes his newest partner. Now it's all up to only ... Written by
Anthony Pereyra <email@example.com>
The dreams that Frank has in the order they are seen are: "Honey, I forgot my pants"; "The Exam" with disclaimer "He didn't study... and the test is in five minutes!"; "Your Worst Nightmare" with Uncle Bob marrying Shane; "Girls from the bus stop". See more »
When Osmosis comes back from "The Zit" he greets Leah by saying "Brandy- oh I mean Leah". Brandy Norwood was the voice of Leah. The error was left in because the director thought it was funny. See more »
We were so poor, we lived off peanut butter and cellulite sandwiches! You ever try to blow-dry your hair with a fart?
OK, I get it. You were poor.
You bet I was! You ever try to make a snowman out of toilet paper cling-ons? Now that's poor!
OK, please, you're going to make me vomit!
Vomit? We couldn't afford no vomit; that's for rich folk.
Excuse me while I wipe my eyes.
Oh, you wanna talk about wiping?
See more »
The Warner Brothers logo comes up looking like a germ-like substance with tentacles (with a blue tint) matching the "feel" of the movie, and is static instead of the modern 3D animated sequence. See more »
Groovejet (If This Ain't Love)
Written by Cristiano Spiller (as C. Spiller), Sophie Ellis-Bextor (as S. Ellis Bextor),
R. Davis, V. Montana, Jr. and R. Walker
Performed by Cristiano Spiller (as DJ Spiller) and Lead Vocals by Sophie Ellis-Bextor (as Sophie Ellis Bextor)
Courtesy of Atlantic Recording Corp.
By Arrangement with Warner Special Products, JT Company (Italy), Blanco y Negro Music (Spain),
Scorpio Music (France), EMI Records Ltd., Kontor Records (Germany) and F&G Management
Contains a sample from Carol Williams "Love is You"
Courtesy of Salsoul Records See more »
I can't believe this movie made such little money it's sad cause it's a very cute and original idea. It's fun to watch how the pill and blood cell travel to different parts of the body. And Bill Murray is good as usual, and Chris Rock's voice fits in with the main character rather well too. I wish the real story could have been put in a little more and the daughter character a little less, plus Chris Elliott is a terrible actor. But overall the movie isn't bad and it's fun and cute, 7/10
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