Frank Detomello is a slovenly zoo keeper, and simple father to the only young and bright girl named Shane, who catches a cold right after he swallowed a germ-ridden egg! The inside of his body is known as the "City of Frank". An unlikely hero of a policeman white blood cell, by the name of Osmosis Jones, works as a member of Immunity cell. But with that germ-ridden egg comes a mortal danger: Osmosis discovers Frank has really contracted a villainous and black-hearted deadly virus known as Thrax who arrives and is plotting to ultimately overheat Frank's body, killing him from the inside out! Thrax is motivated by trying to become the nastiest new virus, attempting to kill each new victim faster than the previous. His grandiose plan for Frank is death in 48 hours, breaking previous medical records! Meanwhile the pill that Frank took, Drix arrives in the body and covers Frank's throat with ice to cover the irritation. Osmosis Jones becomes his newest partner. Now it's all up to only ... Written by
Anthony Pereyra <email@example.com>
Early in the movie, Thrax was referred to as "La Muerte Roja" (The Red Death). This was the name of the killer plague in Edgar Allan Poe's short story "The Masque of the Red Death" (The Mask of the Red Death). See more »
During the beginning when Ozzy is patrolling the mouth in a helicopter, there is a shot where some of the bubbles of egg and saliva very quickly shift position. This is likely an animation error. See more »
Don't you ever think about anyone other than yourself?
I think about you all the time.
Were you thinking about me when you packed me a fried Slim Jim sandwich for lunch?
Yeah, it was a turkey Slim Jim!
See more »
The title appears as bubbles, which then pop after 5 seconds. See more »
Osmosis Jones is a comedy of human proportions, I guess. It works enough and when it works well it's a good movie. Although when you think about it the plot-line inside Frank's body (frank is played by Bill Murray with no shame in great form) is rather routine and for me was the only thing keeping this from being really good.
Still, it might be a worthwhile movie, more for kids than adults, but it it watchable for all. Various voices include Chris Rock, Brandy Norwood, Laurence Fishburne, David Hyde Pierce and William Shatner. Pleasant most of the way and sometimes cool. B
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