Frank Detomello is a slovenly zoo keeper, and simple father to the only young and bright girl named Shane, who catches a cold right after he swallowed a germ-ridden egg! The inside of his body is known as the "City of Frank". An unlikely hero of a policeman white blood cell, by the name of Osmosis Jones, works as a member of Immunity cell. But with that germ-ridden egg comes a mortal danger: Osmosis discovers Frank has really contracted a villainous and black-hearted deadly virus known as Thrax who arrives and is plotting to ultimately overheat Frank's body, killing him from the inside out! Thrax is motivated by trying to become the nastiest new virus, attempting to kill each new victim faster than the previous. His grandiose plan for Frank is death in 48 hours, breaking previous medical records! Meanwhile the pill that Frank took, Drix arrives in the body and covers Frank's throat with ice to cover the irritation. Osmosis Jones becomes his newest partner. Now it's all up to only ... Written by
Anthony Pereyra <email@example.com>
Although Thrax is considered to be a dangerous virus, it is never clarified throughout the film what type he is. See more »
In the scene where Frank converses with the oyster boy, the latter says something about 'the oysters should be edible...if my hypothenuse is correct'. The correct line is 'if my HYPOTHESIS is correct.' See more »
Who are you?
Who am I? Who am I? Ah, Bad Booty-shaking Pickanosis, yeah! That's who I am!
Never heard of ya!
That's 'cause you just got here! You ask any of these suckers, when it comes to illin', Bad Booty-shaking Pickanosis stands avove all the rest!
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The opening credits are shown on strands on amoeba. See more »
I thought this movie was very good. The people leaving bad reviews are being too critical. This movie was meant to be fun. The way the inside of the body is a city, the white blood cells are the police, fireman, etc., the lymph nodes were the police stations, veins were highways, the stomach was a bus station/airport type place, and the germs and bacteria were, of course, the criminals, and so on. This movie gives a very imaginative way the body works to fight infection, as if the body was a city of people just like in the real world. You may need to have some sort of knowledge about the body to get some of the puns and jokes, maybe not very young kids will get it, but they will like the animation...this movie is even good for adults. I give the movie 8/10...I thought it was a very entertaining movie!!!!!
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