Down 9 this week

Osmosis Jones (2001)

PG  |   |  Animation, Action, Adventure  |  10 August 2001 (USA)
Your rating:
    1 2 3 4 5 6 7 8 9 10 -/10 X  
Ratings: 6.2/10 from 24,205 users   Metascore: 57/100
Reviews: 123 user | 81 critic | 28 from Metacritic.com

A policeman white blood cell, with the help of a cold pill, must stop a deadly virus from destroying the human they live in, Frank.


Watch Trailer
0Check in

Watch Now

From $2.99 on Amazon Video

1 win & 7 nominations. See more awards »



Learn more

People who liked this also liked... 

Stuck on You (2003)
    1 2 3 4 5 6 7 8 9 10 5.8/10 X  

Conjoined twins from Martha's Vineyard move to Los Angeles so that one of them can pursue an acting career.

Directors: Bobby Farrelly, Peter Farrelly
Stars: Matt Damon, Greg Kinnear, Eva Mendes
Shallow Hal (2001)
Comedy | Drama | Fantasy
    1 2 3 4 5 6 7 8 9 10 5.9/10 X  

A shallow man falls in love with a 300 pound woman because of her "inner beauty".

Directors: Bobby Farrelly, Peter Farrelly
Stars: Jack Black, Gwyneth Paltrow, Jason Alexander
Kingpin (1996)
Comedy | Sport
    1 2 3 4 5 6 7 8 9 10 6.9/10 X  

A star bowler whose career was prematurely "cut off" hopes to ride a new prodigy to success and riches.

Directors: Bobby Farrelly, Peter Farrelly
Stars: Woody Harrelson, Randy Quaid, Bill Murray
    1 2 3 4 5 6 7 8 9 10 7/10 X  

A successful psychotherapist loses his mind after one of his most dependent patients, a manipulative, obsessively compulsive narcissist, tracks him down during his family vacation.

Director: Frank Oz
Stars: Bill Murray, Richard Dreyfuss, Julie Hagerty
Action | Adventure | Comedy
    1 2 3 4 5 6 7 8 9 10 6.1/10 X  

When missile technology is used to enhance toy action figures, the toys soon begin to take their battle programming too seriously.

Director: Joe Dante
Stars: Kirsten Dunst, Gregory Smith, David Cross
    1 2 3 4 5 6 7 8 9 10 5.9/10 X  

Four small-time two-bit character actors, all close friends, are competing for same important part in the next Martin Scorsese mob film.

Director: Philip Frank Messina
Stars: Adam Arkin, David Strathairn, Jon Tenney
Scrooged (1988)
Comedy | Drama | Fantasy
    1 2 3 4 5 6 7 8 9 10 7/10 X  

A selfish, cynical T.V. executive is haunted by three spirits bearing lessons on Christmas Eve.

Director: Richard Donner
Stars: Bill Murray, Karen Allen, John Forsythe
Comedy | Romance
    1 2 3 4 5 6 7 8 9 10 5.8/10 X  

A female marriage counselor and a male depression expert try to solve the marital problems of a troubled couple.

Director: John McNaughton
Stars: James Spader, Melora Walters, Jay Mohr
Caddyshack (1980)
Comedy | Sport
    1 2 3 4 5 6 7 8 9 10 7.4/10 X  

An exclusive golf course has to deal with a brash new member and a destructive dancing gopher.

Director: Harold Ramis
Stars: Chevy Chase, Rodney Dangerfield, Bill Murray
Animation | Comedy | Drama
    1 2 3 4 5 6 7 8 9 10 5.4/10 X  

Davey Stone, an alcoholic with a criminal record, is sentenced to community service under the supervision of an elderly referee. Davey is then faced with trying to reform and abandon his bad habits.

Director: Seth Kearsley
Stars: Adam Sandler, Rob Schneider, Jackie Sandler
Shanghai Noon (2000)
Action | Adventure | Comedy
    1 2 3 4 5 6 7 8 9 10 6.6/10 X  

A Chinese man who travels to the Wild West to rescue a kidnapped princess. After teaming up with a train robber, the unlikely duo takes on a Chinese traitor and his corrupt boss.

Director: Tom Dey
Stars: Jackie Chan, Owen Wilson, Lucy Liu
Get Smart (2008)
Action | Adventure | Comedy
    1 2 3 4 5 6 7 8 9 10 6.5/10 X  

A highly intellectual but socially awkward spy is tasked with preventing a terrorist attack from a Russian spy agency.

Director: Peter Segal
Stars: Steve Carell, Anne Hathaway, Alan Arkin


Cast overview, first billed only:
Osmosis Jones (voice)
Thrax (voice)
Drix (voice)
Leah (voice)
Tom Colonic (voice)
Kidney Rock (voice)
Kenny Olson ...
Kidney Rock (voice)
Jason Krause ...
Kidney Rock (voice)
Kidney Rock (voice)
Stefanie Eulinberg ...
Kidney Rock (voice)
Jimmie Bones ...
Kidney Rock (voice)
Uncle Kracker ...
Kidney Rock (voice)
Additional Character Voice (voice)
Additional Character Voice (voice)


Frank Detomello is a slovenly zoo keeper, and simple father to the only young and bright girl named Shane, who catches a cold right after he swallowed a germ-ridden egg! The inside of his body is known as the "City of Frank". An unlikely hero of a policeman white blood cell, by the name of Osmosis Jones, works as a member of Immunity cell. But with that germ-ridden egg comes a mortal danger: Osmosis discovers Frank has really contracted a villainous and black-hearted deadly virus known as Thrax who arrives and is plotting to ultimately overheat Frank's body, killing him from the inside out! Thrax is motivated by trying to become the nastiest new virus, attempting to kill each new victim faster than the previous. His grandiose plan for Frank is death in 48 hours, breaking previous medical records! Meanwhile the pill that Frank took, Drix arrives in the body and covers Frank's throat with ice to cover the irritation. Osmosis Jones becomes his newest partner. Now it's all up to only ... Written by Anthony Pereyra <hypersonic91@yahoo.com>

Plot Summary | Plot Synopsis


He's one cell of a guy. See more »

Motion Picture Rating (MPAA)

Rated PG for bodily humor | See all certifications »

Parents Guide:





Release Date:

10 August 2001 (USA)  »

Also Known As:

Agent Bílá krvinka  »

Filming Locations:

Box Office


$75,000,000 (estimated)

Opening Weekend:

$5,271,248 (USA) (10 August 2001)


$13,596,911 (USA) (5 October 2001)

Company Credits

Show detailed on  »

Technical Specs


Sound Mix:

| |



Aspect Ratio:

2.35 : 1
See  »

Did You Know?


In the bladder sequence, you can see one of the characters carrying Pikachu of the Pokémons as a pet. See more »


When Shane decides not to go to Buffalo with Frank, we see the ticker above his door showing the scores of various sports games. The item "Seattle: 5 Oakland: 4" scrolls onto the screen in two consecutive shots. See more »


Latino germ: La Muerte, man! Esta aqui! He's gonna kill us dead, hombre!
Osmosis: No, no. Talk English, man. We ain't on Telemundo here.
See more »

Crazy Credits

The Warner Brothers logo comes up looking like a germ-like substance with tentacles (with a blue tint) matching the "feel" of the movie, and is static instead of the modern 3D animated sequence. See more »


Edited into Ozzy & Drix: Home with Hector (2002) See more »


Groovejet (If This Ain't Love)
Written by Cristiano Spiller (as C. Spiller), Sophie Ellis-Bextor (as S. Ellis Bextor),
R. Davis, V. Montana, Jr. and R. Walker
Performed by Cristiano Spiller (as DJ Spiller) and Lead Vocals by Sophie Ellis-Bextor (as Sophie Ellis Bextor)
Courtesy of Atlantic Recording Corp.
By Arrangement with Warner Special Products, JT Company (Italy), Blanco y Negro Music (Spain),
Scorpio Music (France), EMI Records Ltd., Kontor Records (Germany) and F&G Management
Contains a sample from Carol Williams "Love is You"
Courtesy of Salsoul Records
See more »

Frequently Asked Questions

This FAQ is empty. Add the first question.

User Reviews

Very fun and imaginative
15 November 2001 | by (United States) – See all my reviews

I thought this movie was very good. The people leaving bad reviews are being too critical. This movie was meant to be fun. The way the inside of the body is a city, the white blood cells are the police, fireman, etc., the lymph nodes were the police stations, veins were highways, the stomach was a bus station/airport type place, and the germs and bacteria were, of course, the criminals, and so on. This movie gives a very imaginative way the body works to fight infection, as if the body was a city of people just like in the real world. You may need to have some sort of knowledge about the body to get some of the puns and jokes, maybe not very young kids will get it, but they will like the animation...this movie is even good for adults. I give the movie 8/10...I thought it was a very entertaining movie!!!!!

23 of 25 people found this review helpful.  Was this review helpful to you?

Message Boards

Recent Posts
What disease is Thrax? jessie-mc
Has anyone else watched this in school? evil_little_olive
How did this flop!? NeoSpike
Ozzie + Leah EMiller152
Elena Franklin grew up to be hot houser-4
It's 1am and it's on ITV why so late? vixsmith1982
Discuss Osmosis Jones (2001) on the IMDb message boards »

Contribute to This Page

Create a character page for: