Manny, Sid, and Diego discover that the Ice Age is coming to an end, and join everybody for a journey to higher ground. On the trip, they discover that Manny, in fact, is not the last of the wooly mammoths.
Frank Detomello is a slovenly zoo keeper, and simple father to the only young and bright girl named Shane, who catches a cold right after he swallowed a germ-ridden egg! The inside of his body is known as the "City of Frank". An unlikely hero of a policeman white blood cell, by the name of Osmosis Jones, works as a member of Immunity cell. But with that germ-ridden egg comes a mortal danger: Osmosis discovers Frank has really contracted a villainous and black-hearted deadly virus known as Thrax who arrives and is plotting to ultimately overheat Frank's body, killing him from the inside out! Thrax is motivated by trying to become the nastiest new virus, attempting to kill each new victim faster than the previous. His grandiose plan for Frank is death in 48 hours, breaking previous medical records! Meanwhile the pill that Frank took, Drix arrives in the body and covers Frank's throat with ice to cover the irritation. Osmosis Jones becomes his newest partner. Now it's all up to only ... Written by
Anthony Pereyra <email@example.com>
Bill Murray's character mentions a "National Chicken Wing Festival" in Buffalo, New York. While the festival did not exist during the filming of the movie, this mention caused organizers to create an annual festival in Buffalo. See more »
On a diagram of Frank's body, the word collarbone is spelled as 'collerbone'. See more »
The Warner Brothers logo comes up looking like a germ-like substance with tentacles (with a blue tint) matching the "feel" of the movie, and is static instead of the modern 3D animated sequence. See more »
Okay, I think I've found the Sadly Underrated Movie of the Year.
I think that, between this and "the Iron Giant", Warner Brothers Animation has GOT to spring for a better promotion department. Really, all they'd have to say is something like: "We just let the creators of 'Something About Mary' and 'Dumb and Dumber' make their own cartoon. Brace yourselves."
All complaints aside, and none of them are really the movie's fault, this is one of the most inventive animated films I've seen in a very long time. The characters and backgrounds are allowed to look and move in ways that are downright refreshingly bizarre. The visuals are very imaginative. The humor, while funny, is still very much what you'd expect from a Farelly Brothers movie that takes place inside a very sick man, so I wouldn't recommend it to little kids or the weak of stomach. If you have a little future A+P major, however, this is going to blow their mind. Give it a look!
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