When Ray and Brenda are in the movie theatre, the preview screen reads: "The following 'Peeview' has been 'assproved' for immature audiences only. If you can read this you are too close. Pee Pee Poopy Boogers Farts Butthole. Rated I for Immature. We thought it would be funny to put this here. Kiss our asses and take it off pause."
In one of the first scenes in Cindy's bedroom. She says, "Would like to have a little bump-bump?" This line was originally written for Scream (1996), but it was later changed to "Would you like to have a little raw footage?"
In the theatrical trailer, one scene shows a close up of a character holding up a chip and saying, "This stuff is good!". In the R-rated version it's revealed the character is actually holding up a joint.
The principal (Principal Squiggman) is played by David L. Lander, who played greaser Squiggy on Laverne & Shirley (1976) (there's a bottle of Schotz beer, from the brewery where Laverne and Shirley worked, in his office). The principal in Scream (1996), which Scary Movie (2000) parodies, was played by Henry Winkler, who played greaser Fonzie on Happy Days (1974).
The script for Scary Movie (2000) is actually a combination of two scripts Dimension Films bought in 1998: "Last Summer I Screamed Because Halloween Fell On Friday The 13th" written by the Wayans brothers and Phil Beauman; and "Scream If You Know What I Did Last Halloween" by Jason Friedberg and Aaron Seltzer. (The latter two are the "two of the six writers of Scary Movie" who went on to make Date Movie (2006), Epic Movie (2007), etc.)
The cameraman played by Dan Joffre is called Kenny. Not only is this a reference to Scream (1996), where the cameraman (W. Earl Brown) in the movie had the same name, but is also the last name of Francis Kenny, Scary Movie's cinematographer.
Most of the brand names seen in the movie have been slightly changed, for example, when the killer is telling jokes to the others there is a character wearing a t-shirt with Toke written in a can printed on it referring to Coke. Also, all of the drinks seen in the fridge have been misspelled, for example Cult instead of Colt.
The "Whassup" scene is a parody of a 1999 Budweiser TV commercial titled "True". The commercial became an inspiration for other Budweiser commercials using the "Whassup" catchphrase up till the year 2002.
Casting directors Mary Vernieu and Anne McCarthy left the film after both a lengthy casting period and over differences with the director. A third casting director, Christine Sheaks, was brought aboard. Sheaks had little to do, since most of the film was cast by Vernieu and McCarthy.
Due to the movie Kazaam (1996) being relatively unknown by the French audience, and despite the fact that Michael Jordan's performance wasn't panned by the critics, the infamous reference to Shaquille O'Neal's acting was changed in the French version: when Carmen Electra's character is asked by the killer what her favorite scary movie is, she replies Space Jam (1996). When told that the film is not a horror movie, she replies, "Yeah, well, you've never seen Michael Jordan act."
James Van Der Beek: Van Der Beek appears at the window when Cindy and Bobby are about to make love, and "I Don't Want to Wait" by Paula Cole plays in the background, which is the theme to Dawson's Creek (1998) which stars James Van Der Beek.
The trivia items below may give away important plot points.
In the scene where Gail is asking whether or not Cindy's dad has been found, which leads to the "swallow" joke again, Gail is hurrying past the police building to get to the sheriffs. If you look at the brick wall in the background, in white spray paint is the name "Doofy", a foreshadow that Doofy is the serial killer.
During the killers stint getting high and making prank calls he says "ki Ki Ki Ma Ma Ma" which sounds like "chi chi chi Ka Ka Ka". It is a reference to the trademark sound peice of the Friday The 13th films.