When his friend Jack disappears the night before his wedding, Detective Michael Colefield looks into it. This draws him into a new world of secret dealings and covert operations. It just so happens there is a war going on between humans and vampires. And now Colefield must choose a side; help his friend who happens to be a vampire, or help the government hunt him down.
A car runs down a woman on a motorbike. The investigation leads Colefield to Danni Ashford, a banker for the vampires, and thence to a small part of the vampire's plan. Colefield seeks Frances Pembroke's advice on how to deal with his newfound job status.
While investigating the attack on a woman who appears to have been saved from her attackers by an apparent vampire, Colefield and Angie find out the woman may be pregnant. The pregnancy appears to be at the direction of the vampires, and the team must determine why.
After a boy kills a priest in school, the team investigate what led up to the attack, and why some of them appear to be infected without having been bitten. The investigation leads them into the world of pedophiles. Meanwhile, Kirsty continues trying to find Colefield.
A man suffering from sickle cell anemia and his sister arrive at the airport from Brazil, looking for Dr. March. As in Robert March, Angies dead husband. As the team tries to sort things out, they discover that the man is infected, and that several crates of "medical supplies" also came in on the flight. Following these supplies leads to serious danger and surprising revelations. Colefield and Kirsty finally meet again.
While the team tries to identify their prisoner and Jacob hiding Kirsty from Colefield, Rice and Colefield both end up searching for Jacob, but for different reasons. Kirsty makes some revelations of her own. Colefield enlists the help of Pembroke, and must make a choice about which side to help.