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James Lipton: What is your least favorite word?
Mark Wahlberg: Is "Marky Mark" one word?

[interviewing the cast of "The Simpsons" as their characters]
James Lipton: Homer, what is your full name?
Dan Castellaneta: Homer J. Simpson. The J stands for Jay.
James Lipton: What do you do at the Nuclear Power Plant?
Dan Castellaneta: I am a safety inspector. I tell people to be safe. And safen up!
James Lipton: Safen up?
Dan Castellaneta: Safen up!
James Lipton: Since you're still here, and Springfield is still here, I assume you have an umblemished record.
Dan Castellaneta: Well... there's a few blemishes on it.
James Lipton: Ever come close to a meltdown?
Dan Castellaneta: Oh, a number of times! If that's what you mean by "blemishes".

James Lipton: What is your favorite curse word?
Jack Lemmon: Cocksucking motherfucker.

[Lipton tries to get De Niro to say "You talkin' to me?"]
James Lipton: The film Taxi Driver. In which, you spoke those immortal words...
Robert De Niro: [uncomfortable] Well, you know... The usual.

Martin Sheen: I love being Spanish as much as I love being Irish, and I *really* love being Irish.

[regarding Lipton's guest appearance on "The Simpsons," in which Ranier Wolfcastle appears on "Inside the Actor's Studio," gets into character as McBain, and shoots Lipton]
James Lipton: Would it have been too much trouble for you to go out and get a prop gun?
Harry Shearer: [as Ranier Wolfcastle] I'm not the prop man. I'm the actor!

[his infamous answer to "if heaven exists, what would you like to hear God say to you when you reach the pearly gates?"]
Harrison Ford: You're much better-looking in person.

James Lipton: What is your favourite word?
Meryl Streep: I... well, y'know, I don't want to lie...
James Lipton: Don't lie.
Meryl Streep: Because I knew that this was coming and so I asked my daughter what her favourite word is and she's six and ever since she said her favourite word, which she said without hesitating, I can't think of anything else...
James Lipton: Say it.
Meryl Streep: Coconut milk.

Meryl Streep: [taking about Out of Africa] Sydney, I remember, didn't think I was sexy enough to play it.
James Lipton: What did you do about that?
Meryl Streep: They didn't have wonderbras in those days, but I wore a padded bra... a push-up bra and a low cut top... isn't that tragic?

James Lipton: I believe you're a man who believes in revenge.
Harry Shearer: [as Montgomery Burns] Yes! Hence the hounds.

[Lipton asks about the seven dirty words]
George Carlin: Shit, piss, fuck, cunt, cocksucker, motherfucker, and tits. That was all I could think of in one sitting.

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