The Thornberrys are in Tanzania, Africa to film the Grand Opening of Dr. Jane Goodall's Chimpanzee Sanctuary. Eliza can't wait to meet her idol Dr. Goodall. When they arrive Debbie is put to work caring for baby chimps in the nursery while Eliza and Dr. Goodall have an awkward first meeting. She is not impressed with Darwin and the fact that he is domesticated. Eliza's feelings are hurt and she runs off into the jungle with Darwin following. Trouble ensues when they run into poachers who have been working nearby.