In Italy a mad scientist invented an earthquake machine that creates massive earthquakes. He demands that the Italy government will pay him a ransom or the Tower of Pisa will crumble. This is where Lupin and his gang come to teach this guy a lesson in not destroying great landmarks. That and try to steal the ransom money from the government.
In Egypt, Lupin steals the death mask of King Tutankhamen. As soon as he starts messing around by wearing it, Lupin ends up being cursed and thinks he's the late ruler of Egypt. Jigen, Goemon, and Fujiko must find a way to cure Lupin.
In Monaco Lupin is going to compete at the Monaco Grand Prix. But when he tries out the casinos in Monaco he lost everything he bet including his own Formula-1 Race Car to a big time business man. So his next strategy is to race for the guy who owns his car while Jigen, Goemon and Fujiko go steal the winning money.
Count Garbiel challenges Lupin to steal his famous carbuncle "Dracula's Tear" on the Hendenburg 2. Garbiel invites 4 detectives to be on patrol on the airship. Sherlock Holmes the 3rd, Detective Archer, Kaneda Koojisuke, and Inspector Koichi Zenigata. The question is how will Lupin and his gang be able to sneak aboard the airship without be seen.
An explosion occurred at an Arab oil Company. And a message was sent to the government in making a deal by dropping off $100,000,000 to a group of terrorists. The group is using remote control capsules to create human bombs whenever you have on in your stomach. Lupin and company decides to get that money for themselves. But it be easy to get especially when the leader of the group claims to be the grandson of Lawrence, Lawrence the 3rd.
In Japan, Marukin safes are one of the most unbreakable safes in the country. Lupin however, manages to crack open the safes. Marukin the head of the company is facing bankruptcy due to the customers finding the safes useless to own. Tetsutaroo (the son of Marukin) challenges Lupin to try to open a safe with no combination or visible door.
In Germany, Lupin plans to steal the chest of a Hitler like leader named Generalissimo Hatler. The chest contains a 50-carat Ruby. But when he accidentally removed Hatler's toupee(which revealed he was bald) made Hatler order an army to wipe out Lupin and his gang. Lupin and Fujiko end up trap in an abandon castle. surrounded by Hatler's army. How will they escape?
Goemon returns to Iga for the first ever in 10 years. He visits his Iga Ninja master, Jinen. But he finds Jinen badly hurt and doesn't have much time left in his life. He tells Goemon that his other student, "Hissatsu Jinkuroo" betrayed him and stole half of the Iga scroll. The scroll contains the secrets of the Iga Ninjas and the location of the Iga Treasure. Jinen gives Goemon the other half of the Map. And Goemon is determine to advantage his master's death. The only trouble is Hissatsu Jinkuroo turned himself in to the police. Because he knew he would stand a ...
Lupin is feeling a little down because he hasn't seen Fujiko for a long time. But then he got a phone call from Fujiko saying that she'll marry him if he passes a test. After that call he takes off and goes to the meeting place where Fujiko is suppose to be at. But instead of Fujiko it's her Aunt Bujiko Mine. She gives him a test in finding Rommel's Gold and if he fails he'll pay for his life. But will Lupin be able to locate Rommel's Gold and see Fujiko again?
Goemon encounters Nezumi-Koozoo IV(Ratboy Jirokichi IV) the fourth decedent of a great thief. He tells Goemon that their ancestors teamed up at the International Thieves' Championship. But they were defeated by Lupin's grandfather Arsene Lupin the 1st. Ratboy suggests Goemon that they should team up and avenge their ancestor's dishonor. And to do that they'll beat Lupin by stealing secret data from the Sakurada Police Station before Lupin gets the chance in nabbing it.
Fujiko is at a prison with less security and no one tries to escape. reason why is because those who escape will get killed by one of these deadly machines called Iron Lizards(Land Sharks). Fujiko sends a letter to Lupin telling him to help her out of the mess she's in. So Lupin, Jigen, and Goemon robbed a bank and let themselves get caught. So that way they can enter the prison without any trouble. But it'll be a lot of trouble when they try to escape with 3 Land Sharks programmed to kill them.
Zenigata is prepared with many different handcuffs to use on Lupin. In Barcelona, Spain Lupin and Jigen are enjoying the night and little do they know is there's a trap involved. When a Spanish female dancer gets kidnapped Jigen goes to rescue her from the con men. Meyer the one who set up the trap has a plan in making Jigen and Lupin see each other as the enemy in disguise. But will either one of them realize that they're up against each other for real?