Because of the show's numerous pop culture references, many of the celebrity guests had already been mentioned on the show before their eventual guest appearances (e.g., Alec Baldwin, Matt Damon, Madonna, Britney Spears, etc.)
Vice President of the United States, Joe Biden, honored the show to be a trailblazer for acceptance of the LGBT community, as well as paving way for endorsement of Same-Sex Marriage; "I think 'Will & Grace' probably did more to educate the American public than almost anything anybody has ever done so far. This is evolving".
Jack's website www.justjack.com really does exist. It now redirects you to NBC's Will & Grace website, but at the time it was created, it was an actual web site created by "Jack." It included pictures and a letter Rosario wrote to the INS.
Originally Max Mutchnick and David Kohan pitched a straightforward couples comedy in which a gay man and his straight female roommate were supporting characters. NBC liked the supporting characters better.
As revealed in an interview, when Megan Mullally learned she won the role, she was leaving NBC studios and made an illegal U-turn. She was pulled over but said it didn't matter because she's on a new show.
Megan Mullally once developed a Broadway musical which revolved around her character on this show, entitled "Karen: The Musical". The musical would be centered on Karen Walker's rivalry with Beverly Leslie, with Leslie Jordan set to appear as well. Mullally secured the rights to the character from NBC, had backing from Fox Theatricals and had lined up a director and a composer for the show, before certain stakeholders in the Karen Walker character withdrew the rights for its use in the production.
One of only three TV series' to win Emmys for all their principal cast-members. The others are All in the Family (1971) and The Golden Girls (1985), with all three shows featuring a regular cast of four.
The Smithsonian's National Museum of American History exhibits memorabilia from the show as a part of documenting the history of LGBT Americans. Featured are original scripts, casting ideas, political memorabilia surrounding the show and the series finale, plus network-donated props such as a sign from "Grace Adler Interior Design," Will Truman's framed college diploma, the portrait of a young man that hung in Will and Grace's New York apartment as well as Karen Walker's pill bottle and flask.
Eric McCormack and Debra Messing would later work again, nine years later, on an episode of Messing's show The Mysteries of Laura (2014). The guest part was written for McCormack, who described working with Messing again to be "like riding a very old, creaky bike."
Karen Walker's husband, Stan, is never entirely seen. However, in Will & Grace: New Will City (2000), viewers do get to see parts of Stan Walker. He reaches out and grabs Karen's breast while she is talking to Will and throughout the scene viewers can see Stan's legs though most of him is blocked by a plant.
In the episode where Grace is going to meet an old high school crush, he says he's part of a group of artists showing their art at the Zelman Gallery. Debra Messing's (Grace) real-life husband is Daniel Zelman.
When Cher and Madonna made their respective appearance on the show, filming of both of their entrances had to be taken several times as uproarious applause from the live action studio audience ruined the audio tracks.
All of the four principal cast won an Emmy in their respective categories over the course of the shows run, with Megan Mullally taking home two for her portrayal of Karen Walker. However, only two years saw all of the cast nominated at the same time, 2000 and 2001. The show managed at least one win in any category, with the exception of two years - The 51st Annual Primetime Emmy Awards (1999), of which it was only nominated in one category, the direction of the pilot, and The 56th Annual Primetime Emmy Awards (2004), in which it was conversely nominated for nine. In only one of it's six nominations did it ever take home the Emmy for Outstanding Comedy Series.
During the episode in which Will and Grace compete for the Tenants Association Presidency, one tenant complains that her missing umbrella closely resembles the one belonging to "Tim Kaiser in apartment 12-B." Tim Kaiser was a producer of the episode.