Bender sets up a successful waste disposal business. But because he dumps everything in the sewers, the Sewer Mutants revolt and sentence Bender, Leela and Fry to be dumped in the Mutagenic Sewage lake. Somehow two robed mutants with an interest in Leela manage to persuade the Supreme Mutant to let them go.
Fry, Leela and Bender are enslaved on the planet of the original Egyptians to build a monument to the Pharaoh. When the Pharaoh dies, Bender rewrites prophecy to take his place, but keeps Fry and Leela as slaves to build an even bigger monument.
Fry learns that Star Trek (1966) was banned on Earth centuries earlier and goes on a quest with Leonard Nimoy's Head to find the last remaining episodes. He encounters the re-embodied cast of the original TV show who are prisoners on the planet of a very devoted fan.
Planet Express is hired to scoop a slab of ice from Halley's Comet and drop it in the ocean to combat global warming. But when they find the comet all out of ice, the inventor of the environment, Al Gore, holds a Global Warming convention. There Professor Farnsworth reluctantly admits the process was sped up by the pollution emissions of all robots. This leads President Nixon's head to invite all of Earth's robots to the Galapagos Islands for a big party (during which they will be destroyed).
Fry's old work place, Panucci's Pizza, has been unearthed and preserved as a museum exhibit. Fry finds the fossilized remains of his dog Seymour and demands to take them home. Professor Farnsworth thinks he can produce a clone of Seymour and inject all of his old memories. But Bender, who has been practicing a magic act with Fry as his lovely assistant, becomes annoyed at Fry for only focusing on his dead dog.