The colors red (Lola's hair, numerous cars, telephone) and yellow (the phone box, supermarket, tram) appear very often in the film, these colors were selected by the director to signify danger. The reds are mainly in Lola's scenes and yellows in Manni's.
Hans Paetsch, who speaks the narration at the beginning, is Germany's most popular fairy tale narrator. His characteristic voice is easily recognized by anyone who grew up with fairy tale records in Germany.
Tom Tykwer hated the empty space on the wall and asked production designer Alexander Manasse to paint a picture of Kim Novak as she was in Vertigo (1958). But Alexander didn't remember what she looked like, so Tom suggested he painted her from behind. Alexander completed the picture within fifteen minutes.
This film contains about 1581 transitions (edits, dissolves, fades, wipes, etc) in 71 minutes of action (i.e. excluding the credits, and pre-credits sequence). This equates to an Average Shot Length of about 2.7 seconds. Interestingly, the editing is relatively slower towards the end of the film. For most contemporary films, the opposite is the norm.
For the shot of the crowd spelling out the title, 300 extras were shot forming each letter separately, and director Tom Tykwer spent about a month compositing the shots together in post-production. It would have taken thousands of extras to spell out the entire title in a single shot, and the production couldn't afford to hire that many.
Yoshiaki Koizumi who is a game-designer at Nintendo(R) called 'Run Lola, Run' one of the main inspirations he had when he came up with the idea behind the game 'The Legend of Zelda - Majora's Mask' (released on Nintendo 64 in year 2000). Like Run Lola, Run, the game is centered around the experience of time rewinding which will make you experience the same days and events reoccur over and over until you eventually have what you need to achieve your main goal.
In the film, Manni needs 100,000 marks. In 1998, the exchange rate for marks was 1.789 making this sum equivalent to $55,897.15 in the US. At the end, Lola winnings amount to 126,000 marks ($70,430.41).
The trivia item below may give away important plot points.
During the third sequence after the head on car collision a moped rider rear ends Ronnies car and lands on the windsheilds. Most viewers do not realize that this is the man who stole Lola's moped, so he gets his comeuppance in the end.