- Senator Kelly's proposal of a Mutant Registration act echoes the efforts of U.S. Congress's efforts to ban Communism in the States. Kelly brandishes a list of known mutants and exclaims "'We must know who these mutants are and what they can do!" an event copied from Senator Joseph McCarthy who claimed to have a list of known American Communists working in the government.
- Kelly further questions whether mutants should be allowed to teach children in school, which mirrors the Section 28 issue (the banning of homosexual teachers in school, which Sir Ian McKellen was involved in).
- a deleted scene has Storm teaching a historical lesson about how Constantine I's conversion to Christianity ended the persecution of early Christians in the Roman Empire, which foreshadows Magneto's plot to force world leaders to accept mutantkind by mutating them.
- Magneto talks about the act having mutants "in chains, with a number burned into their forehead" - the situation he describes is similar to what happened to the Jews in Nazi Germany (Magneto himself is a World War II survivor)
- Magneto's last lines contain the phrase "By any means necessary." This phrase was coined by civil-rights revolutionary Malcolm X; the relationship between Magneto and Professor X has been compared, respectively, to that of Malcolm X and Martin Luther King, both of whom held differing philosophical views.