During an engine cool down break from hyperspace travel the crew of the Prometheus, with Major Carter as an advisor, encounter a space craft of unknown configuration. They hail the ship to no avail; the unknown craft opens fire upon the Prometheus. Carter attempts to override the safety protocols on the hyperdrive to make a short jump into a gas cloud, but in the attempt is knocked unconscious. She awakes to find the ship devoid of all its crew and, as she tries to escape the gas cloud by herself, she begins to hallucinate.
Jonas Quinn returns to SGC to ask for assistance in saving his nation. He explains that the Naquadriah was originally Naquadah and a Goa'uld started a chain reaction to transform all of his planet's Naquadah into Naquadriah. A large vein of Naquadah has just been affected and the Kelownan scientists believe that the transformation will cause this large a deposit to explode, taking their entire nation with it.
Maj. Carter has been set up with her brother Mark's friend Pete Shanahan, a cop from Denver who thinks Carter works for the Air Force in a simple research capacity. Daniel Jackson is being visited in his dreams by his former lover, Sarah Gardner, who was possessed by the Goa'uld system lord Osiris.
At the new Alpha site, Sam Carter and Selmak (the symbiote carried by Jacob Carter, her father) are working on a new weapon to defeat the Anubis superdrones when the planet is attacked by a fleet of Goa'uld ships. Carter escapes with the prototype weapon before the base auto-destruct is activated but finds herself being pursued by a superdrone.
The president has asked a documentarian to SGC to create a film about its operations. His arrival is unwelcome to most and he begins to clash with the base personnel. Nevertheless, he conducts his interviews with SG-1 and the scientists in the employ of SGC. Meanwhile, an off-world SG team finds the remains of an Ancient city.
The documentarian still a thorn in their side, SGC encounters an unforeseen predicament. With half of SG-13 off-world engaging enemy Jaffa, SG teams 1, 5, and 7 go in as backup. In the midst of heavy fire, O'Neill takes a staff blast to the chest. Many deaths from the encounter hit SGC hard and Senator Kinsey orders a full investigation into the matter.
Agent Barrett of the NID calls SG-1 to Los Angeles for a consult on a mass murdering of a rogue sleeper cell by a young woman. There they find many Goa'uld artifacts relating to Sekhmet, a subordinate of Ra. But how this operation is related to the Goa'uld eludes SG-1.
The newly inaugurated President of the United States is briefed by the Head of the Joint Chiefs of Staff on the Stargate program. Former Senator, now Vice President, Kinsey attempts to get his running mate to back his policies for the program, but the president decides to look into the situation himself. Kinsey gets Richard Woolsey to convince the president of his agenda.
Vice President Kinsey briefs Dr. Weir on the Stargate program before her meeting with the president. SG teams 1, 3, and 5 go off-world to attempt the extraction of a newly found Ancient repository device. Upon arriving at the location of the device, SG-1 comes under fire from Goa'uld ships. With no other way to disallow Anubis from claiming the knowledge for himself, Jack submits himself to the dangerous device.
With Jack having the knowledge of the Ancient repository once again in his mind, he and Daniel attempt to unearth the location of the lost city of the Ancients. Bra'tac, bringing with him the news of an impending attack on the Tau'ri by Anubis, takes Teal'c to help him acquire ships and warriors for the defense of Earth. Dr. Weir attempts to cope with the overwhelming nature of her new job, while also dealing with the unrelenting ego of Vice President Kinsey.
In a last ditch effort, O'Neill activated an Ancient weapon in the Antarctic to defeat Anubis. With Jack still in stasis in the Ancient outpost buried in Antarctica, SG-1 tries to contact the Asgard. Meanwhile their new leader, Dr. Elizabeth Weir, tries to decide what to do about a request for peace talks from the Goa'uld System Lords.
The Asgard fleet has managed to destroy the Replicator ship, with Carter aboard, but cannot contain the debris. Talks break down with the System Lords, ending in a Ha'tak being dispatched to test Earth's new defensive capabilities. The Prometheus waits to engage the incoming enemy, but Thor arrives in the Daniel Jackson, with Teal'c aboard. They enlist the help of Daniel and Jack, still in stasis, to remove the threat of the replicators to the new Asgard homeworld.
General O'Neill is still in the early days of commanding the SGC and faces a major problem when newly arrived Russian Col. Alexi Vaselov collapses in his quarters. Dr. Brightman's belief that Vaselof may be contagious seems correct when Daniel, who was with the Russian when he collapsed, apparently goes mad and tries to leave the base through the gate. O'Neill locks down the SGC but the problem isn't contagion: the essence of Anubis is alive and well and seeking a new host.
Dr. Lee is adapting a virtual reality chair for use as a training device. Teal'c thinks its current scenario is all too easy and agrees to work with them to make it more realistic. He enters the game scenario and is quickly "killed" at which point the chair shocks him. Lee says it must be part of its basic construct. As the scenario resets - it's an invasion of SGC by Goa'uld - Teal'c is repeatedly killed and shocked putting him in danger. The computer program is set up to learn after each scenario and the challenge for Teal'c increases at every turn. Daniel ...
Having obtained permission to live off the base, Teal'c rents an apartment telling neighbors that he has recently arrived from Mozambique. He's under orders to keep a low profile but can't seem to help himself when it comes to helping his neighbors. He helps one of who is about to be assaulted by three thugs but it's his next door neighbor who seems to need assistance. Krista is having problems with her boyfriend Doug. Teal'c soon realizes that he is beating her and warns him that should he hurt her, Teal'c will kill him. It all becomes very difficult when Doug is ...
Owner and CEO of Colson Industries declares in a press conference that there is alien life and that he has proof. SGC fails in its attempts to keep him quiet on the battle over the Antarctic. However, they are greatly surprised when the proof he shows the media are not his satellite images, but a living Asgard.
Teal'c is unhappy with his son's plans to marry. Ishta arrives bringing news that Hak'tyl may be compromised. Complications arise when O'Neill allows Hak'tyl to inhabit SGC until a new homeworld is found for them.
General Hammond returns to SGC to take Dr. Jackson with him on a trip to Atlantis onboard the Prometheus. In the middle of their trip, the Prometheus picks up a distress signal and Hammond decides to investigate. Things get sticky when a Kull Warrior takes control of the Prometheus, leaving Hammond and his crew, minus Daniel Jackson, behind in a damaged Alkesh.