At one point Johnny's brain implant is detected by a security scanner and is falsely reported as a device for counteracting dyslexia. Ironically Keanu Reeves does in fact suffer from the disorder in real life.
The film was shot on location in Canada, with Toronto and Montreal filling in for the film's Newark and Beijing settings. A number of local sites, including Toronto's Union Station and Montreal's skyline and Jacques Cartier Bridge, feature prominently.
During the scene in the back room of Crazy Bob's Computer Store it sounds like Johnny asks for an "iPhone", 12 years before it was launched - while it would still be cute if the script writer of a 90's cyberpunk movie had just made up a word which would later become the name of a ubiquitous piece of information technology, what Johnny asks for is actually an "Eyephone", an early head-mounted interface designed by Jaron Lanier (in fact, Johnny calls it a "Thomson Eyephone", a reference to the fact that Lanier's patent was bought by Thomson Electronics).
Three music scores were created for the film. The first, composed by the band "Black Rain" at the request of director Robert Longo, was not used in the film and was subsequently released on a CD album. The second was composed by Mychael Danna and is still featured in the Japanese version of the film. The third score was composed by Brad Fiedel at the request of Sony and is featured in the internationally released version of the film.
The character Molly Millions, from the original story, was changed to Jane for the film. They are very similar characters except that Molly had retractable razor blades under her fingernails and augmented vision. It is believed that the change was due to the "Molly" character being attached to the rights for any possible future Neuromancer film adaptation.
In this film, Keanu Reeves plays a man who smuggles data from cyberspace. 4 years later, Keanu Reeves starred as a computer hacker who learns that he has been living in a computer program in "The Matrix".