Six years ago, Michael Myers terrorized the town of Haddonfield, Illinois. He and his niece, Jamie Lloyd, have disappeared. Jamie was kidnapped by a bunch of evil druids who protect Michael Myers. And now, six years later, Jamie has escaped after giving birth to Michael's child. She runs to Haddonfield to get Dr. Loomis to help her again. Meanwhile, the family that adopted Laurie Strode is living in the Myers house and are being stalked by Myers. It's the curse of Thorn that Michael is possessed by that makes him kill his family. And it's up to Tommy Doyle, the boy from Halloween, and Dr. Loomis, to stop them all.
Sixth in the series and the fifth to feature the character of Michael Myers. It has been six years since both Michael and Jamie disappeared from Haddonfield's Police Station. Now, in 1995, the kids of Haddonfield want to have parties on Halloween Night again after their parents have banned it since the incidents of 1988 (H4) and 1989 (H5). Meanwhile, Jamie has been raped by a cult but manages to escape with her new-born baby. But Michael in hot pursuit. The Strode family has moved into the Myers' house, in an attempt to break the curse and to finally sell the house. But daughter Kara Strode has problems with her son, Danny Strode who is haunted by the Man in Black (from H5). Help is at hand though from not only Dr. Loomis but also from an unexpected source, Tommy Doyle (one of the two child survivors from H1). Tommy has grown up and has researched into Michael's madness and he might have the answer...
Six years after Michael Myers last terrorized Haddonfield, he returns there in pursuit of his niece, Jamie Lloyd, who has escaped with her newborn child, for which Michael and a mysterious cult have sinister plans.
- On October 31, 1989, Michael Myers and his niece Jamie Lloyd (Danielle Harris) have been abducted by a mysterious stranger in black at the Haddonfield Police Station. Six years later, teenage Jamie (J. C. Brandy) has been impregnated and her baby is born on Halloween Eve. The baby is taken away by the "Man in Black" who appears to be the leader of a Druid-like cult. Later, a midwife (Susan Swift) helps Jamie escape with her baby and is soon killed by Michael (George P. Wilbur). Jamie and her baby flee in a stolen pickup. Stopping briefly at a deserted bus station, Jamie makes a call to a Haddonfield radio station to warn them that Michael is about to return home, only to be ignored by the radio D.J. Barry Simms (Leo Geter) who is doing a broadcast on the Haddonfield murders.
Meanwhile, a frail Dr. Loomis (Donald Pleasence), now retired and recovering from a stroke, is visited by his friend Dr. Terence Wynn (Mitch Ryan), the chief administrator of Smith's Grove Sanitarium where Michael had been incarcerated as a boy, who asks Loomis to return to Smith's Grove. During their conversation they overhear Jamie's plea for help on a local radio station. Later, Jamie drives back on the road followed by Michael, who causes her to crash into an old barn. Michael kills Jamie by impaling her on a corn thresher, but finds that Jamie's baby is not in the truck.
Back in Haddonfield, Tommy Doyle (Paul Rudd), whom Laurie Strode babysat in the first film, now lives in a boarding house run by Mrs. Blankenship (Janice Knickrehm), a mysterious old woman. The family living in the Myers house across the street are relatives of the Strode family: Kara Strode (Marianne Hagan), her six-year-old son Danny (Devin Gardner), her teenage brother, Tim (Keith Bogart), caring mother Debra (Kim Darby) and abusive father John (Bradford English). Ever since seeing Michael Myers as a child, Tommy has been obsessed with finding the truth behind his motives. He finds Jamie's baby at the bus station, takes him into his care and names him Stephen. Tommy runs into Dr. Loomis and tells him that the Strode family living in the Myers house. The two believe Michael has returned to Haddonfield.
After Dr. Loomis tells her that she is living in Michael's home, Debra calls John to tell him she wants to leave Haddonfield but is killed by Michael. Later, Kara returns home to find Danny in his room with Tommy, whom he had met while on his way home. The three go to the boarding house, where Tommy reveals that he believes Michael has been inflicted with the curse of Thorn by a Druid-inspired cult. Thorn is an ancient Druid symbol that represented a demon that spread sickness and caused destruction. To prevent this, one child from each tribe was chosen to bear the curse of Thorn to offer a blood sacrifice of its next of kin on the night of Samhain (Halloween). When the corresponding Thorn constellation appears, Michael appears. The curse explains why Michael is out to kill his family and also accounts for his superhuman abilities. Tommy believes that Steven will be Michael's final sacrifice.
While Tommy goes out to look for Dr. Loomis at a party at the Haddonfield Junior College, Mrs. Blankenship reveals to Kara that she was babysitting Michael the night he killed his sister, and that Danny hears the "voice" (from the "Man in Black") telling him to kill just like Michael did, indicating that Danny also possesses the power of Thorn. Meanwhile, Michael kills John and Tim Strode, Tim's girlfriend Beth (Mariah O'Brien), and Barry Simms. After Tommy returns home with Dr. Loomis, the "Man in Black" finally reveals himself to be Dr. Wynn. The "Cult of Thorn" take Kara, Danny, Steven, and Michael to Smith's Grove. There, Loomis confronts Dr. Wynn who credits Loomis for first recognizing the evil power of Thorn inside Michael, which Wynn wants to control and study, and that Jamie's baby represents the dawn of a new age. Loomis is then knocked unconscious by a staff member.
Tommy finds Kara locked in a room in the maximum security ward and frees her. In one of the main hallways, they see Wynn and a team of scientists walk into an operating room to perform an unknown procedure. Tommy and Kara sneak into the adjoining room where they find Danny and Steven. Michael, angry at being exploited by Wynn and his staff, walks into the operating room with a surgical machete and murders them all. Tommy, Kara, and the kids run with Michael in hot pursuit, and hide in a high-tech laboratory. Inside the lab, Kara notices tanks containing human fetuses with a chart of runes and scientific letter codes connected together by the Thorn symbol, suggesting that the cult of scientists have been exploiting the evil power of Thorn for the benefit of medical science. It is implied that they have been trying to clone pure evil using the desired genes that Michael possess by impregnating their female patients to replicate Thorn in its most powerful form. Steven is the result of this experiment tested on Jamie.
Michael breaks into the room. Tommy injects him with a corrosive liquid and beats him into unconsciousness with a lead pipe. As Dr. Loomis, Tommy, Kara, Danny, and Steven are about to escape, Loomis tells them to go on without him because he has "a little business" to attend to. Back inside the building, Michael's mask is found lying on the floor of the lab room as the screams of Dr. Loomis can be heard in the background, leaving his fate ambiguous.