Vledder is deeply shocked when his present girlfriend, newspaper reporter Renee Goes, is found murdered in a parking lot. It gets worse as the investigation suggests she was sleeping around with the growing lists of potential suspects, some of whom were implicated in a drug network she intended to report to him. Vledder can't control his doubly-motivated hostility to his rivals-suspects, so he has to be suspended. A suspect drug-pusher escapes from the precinct after pointing at a a rival gang, only to be found presumably pushed down from a high balcony.
De Cock and his team investigate the death of a woman who fell out the window at the house of a rich family. They discover that her rebellious attitude wasn't popular with all members of the conservative family.
Lowietje's nephew is found dead in Lowietje's café. De Cock and his team investigate, and discover that he was working in the kitchen of a star restaurant. To De Cock's grief, his good friend Lowietje is also a possible culprit.
De Cock and his team investigate the murder on a man dressed in St. Nicholas clothes. They discover that he and his ex-wife were fighting over their young daughter, and his new girlfriend was having an affair.
Shipyard owner Ronald ten Bosch is found fatally hit with wood just before his intended wedding. The notary points out that prevents the finalizing of his new will, which provided a competition between his bitterly opposed twin sons Alex and Kasper for control of the firm, while widow Ilse, who claims it was her idea, negotiated a shares sale to competitor Douma, whose wife's affair with Ronald wasn't the only suspicious one. Keizer meanwhile is abused by women after a drunken memory-lapse.
Fifteen years ago, then junior detective De Cock's senior colleague Frank van der Meulen was retired early for obsessing about his never substantiated theory that youth friend Elisabeth's suicide was murder. After a nightmare about Frank, De Cock goes see him, only to hear he died the day before from cardiac arrest while jogging with friend Joop van Klaveren, MD. Without legal cause, De Cock gets Den Koninghe to perform an informal autopsy, which shows fatal atropine poisoning. De Cock now looks into Frank's theories, rekindled by the new possibilities of DNA tests. ...