In Chicago Hope: Cutting Edges (1995), the series quietly broke a major network TV taboo by showing the uncensored breasts of a teenage girl after her character undergoes successful reconstructive surgery. The scene, conducted with no fanfare and in good taste, attracted little controversy.
Premiered on a Thursday in the US, the same night as ER (1994). "Hope" was trounced in the ratings and moved to another night. Actors Noah Wyle and Peter Berg appeared on each others shows in an uncredited or voice-over roles. In one storyline, "Hope" did a commercial that looked exactly like the opening credits to "ER."
There are a lot of references throughout the series to St. Elsewhere (1982) another popular hospital-themed drama. Kate Austin wins the "Left Anterior Descending Aorta" award for being a top notch cardiac surgeon. Stephen Furst appeared playing a vet named Elliot. On St. Elsewhere he played Elliot Axelrod whose father was a vet (he did not appear as his actual St. Elsewhere character though as Elliot Axelrod, he was killed off in St. Elsewhere). And Kate quotes her mentor to be "Dr. David Demidian." Mark Craig ('William Daniels' ) on St Elsewhere said that Demidian was his mentor as well.
During the show's run, Cadillac ran a series of ads for it's new mid-size sedan, imploring people to "...lease a Catera." Then, the announcer would ask, "Who *is* Lisa Catera, anyway?" Shortly thereafter, Stacy Edwards joined the cast...playing Dr. Lisa Catera (1997-1999)
Many members of the cast have gone on to work together on other series. Mark Harmon, Rocky Carroll and Lauren Holly have all had starring roles on NCIS, while Roma Maffia and Stacy Edwards have appeared in guest roles. Thomas Gibson and Mandy Patinkin appear together in Criminal Minds. Adam Arkin, Hector Elizondo, Rocky Carroll, Mark Harmon, Ron Silver and Roma Maffia all appear in various roles in The West Wing. John DiMaggio and Lauren Tom both provided voices for Futurama.