Sharon Stone was initially set to play the role of Harriet Michaels, but wanted to perform a dual role and also play Rose Michaels. The studio denied her request and she pulled out of the film altogether.
While shooting scenes in the butcher shop, Nancy Travis was distracted by Mike Myers' antics and accidentally cut off the tip of her middle finger on her left hand when chopping vegetables with a kitchen knife. A local doctor sewed it back on.
The soccer game that Stuart MacKenzie tells "Head" to turn on is a friendly match between the USA men's soccer team and Scotland that took place in Denver, Colorado on May 17, 1992 at Mile High Stadium. Scotland won, 0-1.
The filmmakers chose San Francisco as the film's setting, citing that it seemed like the ideal place for Charlie the poet to live. Mike Myers admired the city's scene for its clothes, music and sensibilities but particularly its coffee-house culture. Myers noted that residents seemed to favor coffee-houses over bars.
The butcher shop used for "Meats of the World" was Prudente Meats on Grant Street in the North Beach Section of San Francisco. Prior to being Prudente Meats it was known as Jacobi Meats, the oldest Kosher butcher in San Francisco. Today, the building houses an art gallery.
The Poets Corner hotel scene was filmed at the Dunsmuir estate, which was also the location for Stacey Sutton's (Tanya Roberts) mansion in the 1985 James Bond movie, A View to a Kill (1985). However, the estate is located in Oakland, California, not north of San Francisco in the mountains, as depicted in this movie.
Charles Grodin and Debbie Mazar both have cameos in this movie: Grodin's car is commandeered by Tony at the end of the movie & Mazar is Tony's date when Charlie & Harriet go on a double date. Both Grodin & Mazar will star in Beethoven's Second the same year as this movie.
The trivia item below may give away important plot points.
In the shooting draft of the screenplay, Harriet was previously married to a German martial arts expert rather than a Russian one. Instead of overhearing two Russian sailors speaking, she overhears a German man proposing to his girlfriend in German.