Lucy Lane moves back into town with her boyfriend Johnny. After Johnny is shot by police during a robbery attempt, two scientists transform him into a cyborg that is powered by Kryptonite. After he discovers this he decides to use his new powerful body to be a more prolific criminal and try to defeat Superman.
After Perry's men's club is robbed and all his savings taken, Lois and Clark begin to investigate and find that the same martial arts expert who robbed the club is responsible for several other robberies. The thief uses special power totem bracelets which allow them to use Superman's strength against him.
Dr. Faraday creates a device that can transmit information to someone's brain through a beam of light and uses it on Lois before he's killed. Two scientists, who are trying to get their hands on the device, make Superman blind with a beam of light shone into his eyes. Lois takes care of him at her apartment, while everybody thinks that Clark is in the mountains with Mayson Drake.
Clark finally asks Lois out on a date, which she accepts after thinking about it for a while. But before they can go out on their first date, Dr. Gretchen Kelly brings Lex Luthor back to life and he begins to work toward getting back his fortune and Lois, by force if necessary.
Television news reporter and Intergang assassin, Diana Stride, decides to find out and expose Superman's secret identity. At the same time, her former partner, Mr. X, decides to turn states witness and she is attempts to silence him before he can name her. Clark must try to protect both himself and Mr. X from her deadly games.
Kyle Griffin (a.k.a The Prankster) escapes from jail using an new weapon that freezes people using a yellow beam of light and resumes harassing Lois. This time he has an added goal, kidnapping the President while he is visiting Metropolis.
Lois and Clark meet H.G. Wells, who has traveled on his time machine with a companion from the future. This companion named Tempus roams the city robbing people of gold, which is needed to fuel the time machine. Wells tells Lois and Clark that future's Utopia was founded by Superman descendants. Tempus wants to destroy Superman, because he finds the future boring. Tempus kidnaps Wells, as he doesn't know how to use the time machine himself. Wells is supposed to take him to 1966 Smallville, where infant Kal-El arrived on Earth. However, they travel to 1866 and not 1966...
Superman is forced to get a lawyer when someone he saves sues him for damages incurred during the rescue. Lois discovers a secret about Dan Scardino's livelihood, and she and Clark decide to have a romantic relationship.
Clark is ready to tell Lois that he's Superman when he is interrupted by Jason Mayzik who has obtained a diary written by Tempus which reveals, among other things, that Clark is Superman. Mayzik kidnaps the Kents who are in Metropolis to celebrate their anniversary, and blackmails Clark into stealing $20 million in diamonds from Mayzik's brother's jewelry store. Mayzik is also working with Lex Luthor's former accomplice, Nigel St. John, who has the Kryptonite that he took from Lex, so that he can kill Superman. Clark robs the diamonds but Lois, who had followed him, ...
Clark asks Lois to marry him. Lois asks "Who's asking Clark or (taking his glasses off) Superman. The secret is out. Lois tells Clark that she figured out his dual identity when he caressed her face the night before. How mad was she? Lois tells Clark she wasn't mad, she was hurt. But then, the more she thinks about it the more she realizes she was mad. Clark tries to explain his reasons for keeping his secret and Lois says she understands but then tells him that he made her think he was two people by lying to her. They hear someone calling for help and Lois tells ...
The Daily Planet receives an invitation to visit an island resort for a review. Perry White decides to send Lois and Clark there. The two lovebirds make a bet to behave like normal people for the weekend. Clark will not use his super powers and Lois will stop working. Things work out fine and the two begin to have real fun until the true intentions of the owner of the resort are unveiled.
On her way home, Lois Lane is abducted and injected with a chip that can order her to do anything. Someone has decided to use her to distract Superman while he steals scientific gadgets. Clark Kent makes the hardest decision of his life. He confronts Lois and says that they must break-up because being with him makes her a target of Superman's enemies.
An old Irish friend of Lois shows up in Metropolis and it is clear that he is head-over-heel in love with her. At the same time, antiques are being stolen from museums and safety deposit box. Clark thinks that Lois's friend is up to no good while she thinks he's just jealous.
A couple who lives next door to Lois Lane disappears. After a bit of investigation, Lois and Clark find that more couples who have been to Larry Smiley's couple camp have also disappeared recently. Perry White decides to send the two reporters to the camp. The situation gets more intense when Perry and Alice also disappear. They have also been to see Larry.
Lois and Clark agree to stop thinking of marriage for the time being as it seems that the idea is causing the two to have nightmarish fantasies about it. Meanwhile, Bad Brain Johnson has escaped jail and is targeting Lois. In reality, someone else is using him and his inventions to capture Superman. Lois is just a bait.
Two sisters try to make Superman apathetic with red kryptonite by shooting its red beam at him so that they could steal $20 million. Because he is hugging Lois, trying to protect her from the beam, his powers are transferred to her. The Kents help create a secret identity to the powerful Lois so she could help people without exposing her real self. This experience opens Lois' eyes to the struggles Clark has been going through all his life trying to save as many people he could and dealing with the ones he wasn't fast enough or strong enough to save.
Just as Lois and Clark are getting romantically closer together, a woman claims on national TV that she is the mother Superman's son, Jesse. The two reporters, against Clark's wish, pursue the story and finds out that Jesse has super powers just like Superman's. Meanwhile, a criminal known as Anonymous is rumored to be in Metropolis.
Two years ago, three Nazi officers woke up from a long sleep to find that they had lost the war to the US. Now, they are trying to set up a new Nazi country in the US as the first step to begin world domination.
Lois and Clark are invited by a computer geek billionaire to experience his new virtual reality program. He manages to trap the two inside the program in order to extract information from Lois about Lex Luthor.
It's almost Christmas and Lois decides not to visit her mother, telling her that she has to cover for Clark who's going to spend Christmas with his parents. It turns out that the Kents are coming to visit their son in Metropolis. Things get very complicated and chaotic when Dr. Sam Lane and Mrs. Ellen Lane pop up at Lois's door. Meanwhile, Mindy Church, the new head of Intergang, is set on killing Superman with a deadly flu from Krypton. Clark becomes really sick from the virus and there are no cure from it on earth. Lois asks her father to help her beloved. The ...