An asteroid is headed for earth and it becomes Superman's mission to stop the impending disaster. He flies into space and intercepts the asteroid at high speed to destroy it. This attempt is only partially successful, and worse Superman seems to be missing and Clark is found with amnesia.
During an interview with an eccentric scientist, Lois unwittingly learns of a great conspiracy to destroy the environment and becomes a witness to her interviewee's murder. Once her story is published, she becomes the target that must be eliminated at all cost. Lois and Clark must race against time to unearth the conspiracy while evading the assassin who has been ordered to kill Lois.
Lois and Clark believe that a string of kidnappings is linked to a magical box decorated with moons and stars. They decide to investigate a magic club where they meet the self-proclaimed greatest magician in the world. Things begin to get serious when the kidnapper manages to hypnotize Superman.
Eugene Laderman, convicted of murdering Henry Harrison, escapes. Then he kidnaps Lois at gunpoint and convinces her he did not commit murder. But if Laderman didn't kill Harrison, who did? The answer lies in a sinister piece of software called The Ides of Metropolis, and in the curious change of personality Harrison's wife experienced after Laderman's conviction.
Clark discovers that the strange orb (first seen in 'Strange Visitor (from Another Planet)' contains recordings made by his father, Jor-El. But he has barely begun to explore them when a young thief steals the artifact and sells it to the worse possible buyer - Lex Luthor.
The Metropolis Star seems able to scoop The Daily Planet on every story. Lois and Clark cannot discover how, until Clark embarks on a plan to investigate the Star and it's publisher Preston Carpenter, a man in the mold of Charles Foster Kane...
Superman saves a crippled jet near Paris... while Clark Kent is in the newsroom of the Daily Planet?!? How can Superman be one place, and Clark another, since they are the same man? And yet, this new Superman seems to have the costume, the powers... everything Superman has. Except, perhaps, the solid moral background of Jonathan and Martha Kent. What he does have is a quite different set of moral codes, taught him by an old adversary of Superman's who means to use the young look-alike to end Superman's career permanently.
Criminals burst into the Daily Planet offices and take most of the employees there prisoner. Only Jimmy manages to escape, eventually finding his way into the ventilation ducts. The criminals want to plunder the secret vault of Prohibition era racketeer Dragonetti, and they'll do it thanks to a set of old blueprints and the information provided by their mysterious boss. Superman risks nuclear catastrophe if he attempts to intervene!
Lex proposes to to a surprised Lois. This in turn also prompts Clark to confesses his love for her. Lois on the other hand confronts Superman about her love for him. Someone detonates a bomb at the Daily Planet forcing the paper to its knees, Perry White to early retirement, Jimmy to unemployment, Jack to jail and Lois into the arms of Lex Luthor.
Lex Luthors ex-wife comes to town determined to revenge the fall of her ex-husband. The target of her revenge is Lois Lane and Superman who in her mind is the two foremost responsible for the faith of Lex Luthor. With her she brings an impostor who through plastic surgery looks exactly like Lois.
Lois gets a bit jealous and insecure after Clark is nominated for a journalism award and she is not. A villain using sound waves as a weapon, is trying to extort the city of Metropolis for half of the money in its banks.
Lois fights a hard struggle to protect one of her sources. When it looks like the source has been murdered as a result of having provided Lois with information Perry feels he has no choice but to suspend her. After some encouragement from Superman it now becomes Lois mission to solve the murder and find out what really happened.
Lois starts to receive gag gifts from a "secret admirer." She and Clark begin to investigate these pranks and discover that behind them is a man who Lois helped send to prison 5 years earlier. He is now out of jail and looking for revenge.
While visiting Lois' Uncle Mike, she and Clark witness gang intimidation and discover that "Intergang", a new criminal organization has moved into and begun to control south Metropolis. Superman becomes powerless to help because of their threats against everyone closest to him. Lois gets jealous when the investigator in charge, Mayson Drake, begins to show interest in Clark.
A general is killed at a demonstration of the army's latest weapon, by that weapon. As Lois and Clark investigate they discover a terrorist plot to high-jack a satellite and that the person behind the plot just might be Lois' best friend from college and her supposedly dead boyfriend.
A scientist who believes he can alter people's personalities using their DNA brings Bonnie Parker, Clyde Barrow, John Dillinger, and Al Capone back using a special cloning process. When Clyde shoots Clark during a confrontation, he must fake his death in order to hide his dual identity.
Superman is struck by lightning while stopping William Wallace Webster Waldecker from committing suicide and his powers are copied into Waldecker transforming him into Respendantman. Superman must now contend with figuring out how this happen and teaching the newest superhero how to use his powers responsibly. Meanwhile, Dr. Gretchen Kelly, Lex Luthor's doctor, witnesses the power exchange and becomes obsessed with getting powers for herself.
After Mr. Schott is fired from his toy making job, he decides to get revenge and make a lot of money by creating Atomic Space Rats, which spray a substance that causes everyone to be more greedy. It also makes adults, including Clark, act like children.