The duo was named after two real people. While going to college, creator Mike Judge lived next door to a destructive, unsupervised 12 year-old who called himself "Iron Butt", as he claimed to feel no pain after challenging others to kick him hard in the rear. One of this boy's friends was nicknamed "Butt-head" by Mike Judge and his classmates. There was another boy who lived a few blocks away named Bobby Beavis, though Judge says that he was absolutely nothing like the character.
Foothill High School in Henderson, Nevada was originally going to be called Highland High School prior to its completion. However the name was changed during production to avoid comparisons to the show.
On the TV series, Butthead and Beavis respectively wear AC/DC and Metallica shirts. But for legal reasons, the captions are changed in most show memorabilia (including DVD cover art). The altered shirts say "Skull" and "Death Rock," respectively by Butthead and Beavis. However, in one episode, Beavis is seen wearing a Slayer shirt.