In the early '70s, some British music shops banned or fined patrons for playing "Stairway to Heaven" because it was played so often. Hence the sign: "No 'Stairway to Heaven'" when Wayne plays the guitar in the store.
The "Stairway to Heaven" guitar riff was changed for the international, cable, and videotape releases to a generic riff because of disputes in obtaining rights to the first five notes of the song, which appear only in the US theatrical release.
There are subtitles when Wayne speaks Cantonese. However, at one point he stops talking, and the subtitles keep coming (This is a play on foreign films where long streams of speech are accompanied by ridiculously minute, concise subtitles.)
"Stan Makita's Donuts", a fictional doughnut shop, is named after the famous Chicago Blackhawks hockey player. The scene's at Stan Makita's were shot at a Tim Horton's, which is in fact a real doughnut shop chain. Horton himself was a famous Canadian Hockey Player. The police officer in the shop is Officer Koharski. This could be a reference to the National Hockey League referee Don Koharski who was told by New Jersey Devils coach Jim Schoenfeld to "have another doughnut, you fat pig" after a playoff game.
During the "Terminator 2" parody scene that has Robert Patrick reprising his role as the evil T-1000 Terminator, the song "Time Machine" can be heard in the background. This song comes from the 1992 Black Sabbath album called "Dehumanizer" which featured a painted image of a Terminator Endoskeleton disguised in a grim reaper costume.
The scene where Wayne's ex-girlfriend Stacy (Lara Flynn Boyle) tries to patch up their relationship by buying him a gun rack, is based on some truth. Mike Myers once dated a girl who apparently broke up with him due to his preoccupation with his comedy. A week later, after some thought, she tried to reconcile by buying Mike a gun-rack. To her, this was an absurd joke that she had hoped Mike would appreciate. He didn't, and the two remained apart. When the movie was released, and Mike's ex viewed the movie with her new steady boyfriend, she was mortified not only to learn that the gun-rack anecdote had been written into the film, but also she was shocked to see that the main characters referred to the Stacy character as a 'psycho hose-beast'. Some time later, Myers telephoned his former girl, attempting to apologize for including a very detracting version of her in the movie.
While filming the Bohemian Rhapsody sequence, both Mike Myers and Dana Carvey developed severe pain in their necks from all the head banging. There are scenes later in the movie where it becomes apparent they are trying to move their necks as little as possible.
Dana Carvey stated in interviews to promote this film during its theatrical run, that he developed severe pain in his jaw due to Garth's overbite, and that he spent his nights after filming had wrapped for the day with bags of ice held to the sides of his face.
When Wayne and Garth are on the hood of the car watching airplanes fly over, Garth asks Wayne if he ever thought Bugs Bunny was attractive in women's clothing. Mike Myers' laugh after that comment was genuine, but he was laughing at something completely different Dana Carvey said off camera.
Following the Alice Cooper scene, when Wayne and Garth are on the Wayne's World set, a Ouija board can be seen in the background on the set in one frame. Cooper was once rumored to have gotten his stage name from a Ouija board.
Wayne Campbell's uniquely American slang proved a challenge for translators into foreign languages (Wayne's line "And monkeys might fly out of my butt!" was translated into Spanish for Latin American audiences as "When Judgment Day comes" [Cuándo llegue el día del juicio.])
Alice Cooper came to the set under the impression that he would be performing musically for the film, with one line. Upon arrival, he was surprised to be handed an entire monologue to memorize and shoot with a small amount of time to do so.
Dana Carvey did not learn the lyrics to "Bohemian Rhapsody" prior to filming the scene where everyone is singing along to it, and was reportedly displeased with the take of that scene used in the film because he was obviously not singing, just moving his mouth in vague relation to the lyrics.