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Lorenzo's Oil (1992) Poster

(1992)

Trivia

Michaela Odone died on June 10th, 2000, of lung cancer. Eight years before her son finally succumbed to ALD.
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Lorenzo Odone, who doctors had predicted would die in childhood, died Friday May 30, 2008 - one day after his 30th birthday.
Zack O'Malley Greenburg (Lorenzo) never acted again after this film.
Don Suddaby (who plays himself in the film) is the actual London biochemist that has synthesized the pure oil (erucic acid) that was used to treat Lorenzo.
Although a medical drama might seem an odd choice for the director of the "Mad Max" movies, George Miller is in fact a qualified doctor.
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Based on a true story.
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Lorenzo is played by six different actors in the film.
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Michelle Pfeiffer was originally cast as Michaela Odone but dropped out in order to play Catwoman in Batman Returns (1992) a role that Susan Sarandon also expressed interest in. The script for "Lorenzo's Oil" was given to Sarandon but she steadfastly refused to read it until she knew that Pfeiffer was no longer participating in the film.
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Laura Linney's movie debut.
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Currently, the only film of George Miller's that doesn't touch upon anything fantastical.
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Lorenzo's actual secretary (Rita Chapman, née Fussey) had an uncredited walk on part in the film.
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George Miller also co-wrote the script. What with his medical background, it lends the film a considerable accuracy when it comes to the progressive symptoms of ALD.
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George Miller's first film since The Witches of Eastwick (1987). It reunites him with Susan Sarandon.
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Nick Nolte says "Bravo" to Susan Sarandon. Jack Nicholson said the same thing to her in George Miller's previous film The Witches of Eastwick (1987).
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