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Lorenzo's Oil (1992) Poster

(1992)

Trivia

Lorenzo Odone, who doctors had predicted would die in childhood, died Friday May 30, 2008 - one day after his 30th birthday.
Don Suddaby (who plays himself in the film) is the actual British biochemist that has synthesized the pure oil (erucic acid) that was used to treat Lorenzo. He was born in the city of Hull, Yorkshire, where he has a street named after him - 'Suddaby Close' - which runs adjacent to 'Lorenzo Way'.
Although a medical drama might seem an odd choice for the director of the "Mad Max" movies, George Miller is in fact a qualified doctor.
Based on a true story.
Michaela Odone died on June 10th, 2000, of lung cancer. Eight years before her son finally succumbed to ALD.
Zack O'Malley Greenburg (Lorenzo) never acted again after this film.
Lorenzo is played by six different actors in the film.
George Miller also co-wrote the script. What with his medical background, it lends the film a considerable accuracy when it comes to the progressive symptoms of ALD.
Michelle Pfeiffer was originally cast as Michaela Odone but dropped out in order to play Catwoman in Batman Returns (1992) a role that Susan Sarandon also expressed interest in. The script for "Lorenzo's Oil" was given to Sarandon but she steadfastly refused to read it until she knew that Pfeiffer was no longer participating in the film.
In a 2014 interview at the Florida Film Festival, Susan Sarandon said that Lorenzo's Oil was originally conceived and shot with the intent that as Lorenzo got sicker and sicker, the movie would fade from color to black and white. However, the production ran out of the money needed to process the film in that way, and the movie ended up being in color from beginning to end. She also said that this was actually the second movie in her career for which this had happened--that originally, the Rocky Horror Picture Show was supposed to be in black and white until the first appearance of Dr. Frank-N-Furter, when his red lips would have been the first item in color in the movie--but again, the production didn't have the money to process the film in that way, so the whole thing stayed in color.
Lorenzo's actual secretary (Rita Chapman, née Fussey) had an uncredited walk on part in the film.
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Laura Linney's movie debut.
George Miller's first film since The Witches of Eastwick (1987). It reunites him with Susan Sarandon.
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Currently, the only film of George Miller's that doesn't touch upon anything fantastical.
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The film cast includes two Oscar winners: Susan Sarandon and Peter Ustinov; and two Oscar nominees: Nick Nolte and Laura Linney.
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This is the only film directed by George Miller that is not part of a larger franchise.
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Nick Nolte says "Bravo" to Susan Sarandon. Jack Nicholson said the same thing to her in George Miller's previous film The Witches of Eastwick (1987).
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