When Ruth buys the farm while still a member of the Red Sox, the seller tells Ruth to "Get those Yankees." There was no big rivalry between the two teams at that time as the Yankees were not really seen as a viable threat to the Red Sox pennant chances. The Yankees-Red Sox rivalry did not really form until sometime after Ruth was sold to the Yankees.
The typefaces for numbers on the Wrigley Field scoreboard (shown when Ruth homers off Charlie Root in the 1932 World Series) use the Federal Highway Administration Series D and E standard alphabets, which weren't created until 1942 and adopted until 1950.
The film portrays Babe Ruth and Lou Gehrig as being enemies from the start. That is, in fact, not the case. When Gehrig first joined the Yankees, he and Ruth got along famously. They would often go on fishing trips and barnstorming tours together in the off season. The Ruth-Gehrig Feud did not start until after Gehrig had married Eleanor Twitchell in 1933.
Contrary to popular belief, Babe Ruth did not hit three home runs in his last game in 1935. While the three-homer game against the Pittsburgh Pirates did occur, Ruth actually retired in between games of a doubleheader against the Philadelphia Phillies a few days later. Babe grounded out in his final at-bat.
Babe Ruth and his first wife, Helen, never divorced because they were both Roman Catholics. They were separated when Babe played for the Yankees as he lived in New York and Helen lived in rural Massachusetts. Babe married Clare Hodgson just a few months after Helen died in a house fire.
Jumpin' Joe Dugan says he got his nickname by "jumping" to whichever team will pay him the most. He actually earned the moniker by teammates due to his habit of taking unauthorized leaves from his team.
Two of the many goofs in the film are the fact that Babe Ruth never hit an infield Homerun as depicted. While he did promise a sick Johnny Sylvester that he would hit a homerun for him he did not meet him in the hospital and he only promised him one homerun, not two as the film depicts.
The film continues the myth that Babe was sold to the Yankees because Red Sox owner Harry Frazee's latest Broadway offering had flopped. In fact, the sale came about due to the fact that Frazee hadn't been hand-picked by American League president Ban Johnson to own a team, hence, Frazee was unwilling to do Johnson's bidding. When Carl Mays jumped the Red Sox, Frazee sold him to the Yankees, ignoring Johnson's order to suspend Mays. Meanwhile, Ruth was out of control, repeatedly breaking curfew, and jumping the team several times. The final straw came when Ruth was a no-show for the final game of the 1919 season, then held out for $20,000, despite the fact that Frazee had given Ruth bonuses. With the White Sox' reputation in tatters following the Black Sox Scandal, and Johnson pressuring the Cleveland Indians, the Detroit Tigers, the Philadelphia Athletics, the St. Louis Browns, and the Washington Senators not to deal with Frazee, Frazee had little choice but to deal with the Yankees.
Babe is shown receiving the news of Miller Huggins death at home during the off season (it is clearly winter). Huggins died in September, 1929 while the baseball season was still in progress, and the news came when Ruth and the Yankees were playing in Boston against the Red Sox.
During a game at Yankee Stadium in 1925, after Ruth strikes out, Lou Gehrig is shown hitting a ball that clears the center field back wall. In fact, no player ever hit a fair ball out of Yankee Stadium during a professional baseball game.
When Ruth asks Colonel Rupert to be made manager of the Yankees or to be released from his contract, Ruth states that Ty Cobb and Tris Speaker are managing. However, the scene takes place in 1934, the year the Yankees released Ruth; both Cobb and Speaker ceased to be managers after the 1926 season, and both were out of the Major Leagues entirely after 1928. Furthermore, Ruth states that he knew the Colonel was looking for a new manager. On his way to managing the Yankees to their fourth consecutive season of at least 90 wins late in the 1934 season, McCarthy's job was never in jeopardy and, in fact, he went on to manage the Yankees for another 12 years.
During the game in which Babe promised the sick child he would hit two home runs, the Yankees were batting in the top of the ninth. But the game was played at Yankee stadium and as home team they should have been batting second.