Stimpy is becoming dangerously stupid. Ren is injected into Stimpy in a race against time to find the problem.When Ren & Stimpy try to collect money from their paper route, Pierre convinces them to grow up and get a man's job - lumberjacking.
Ren & Stimpy go to the Natural History Museum to see the skeletal remains of the mammoth Stimpysaurus. Wilbur Cobb tells them about the evolution of the great beast and says that even the meat-eating Renosaurus couldn't conquer the huge bumbling idiot.
In a deranged tribute to the "I Love Lucy" show, Stimpy lavishes affection on a store-bought oven-ready chicken. Next, Powdered-Toast Man and Waffle-Woman face off in a fight-to-the-death; the world hangs in the balance.
Ren and Stimpy find themselves in elf and gnome world where everyone happily works to graduate Pixie status. Stimpy loves his new work, but Ren thinks it's too hard and everyone is too happy. Ren decides instead that he wants to become a pixie king.
Wilbur Cobb tells a campfire story about Galoot Wranglers. Ren and Stimpy play the part of the galoot wranglers.Ren goes crazy and is sent to a home. Here we see the whole cast of the Ren & Stimpy show has gone nuts.