20th Century Fox drastically cut this film at the last minute prior to its theatrical release, omitting most of the more graphic violence and completely deleting rock singer Suzi Quatro's role from the final print. Moreover, the movie was misleadingly advertised as just another standard slasher feature.
In the Bible, Midian was the land in which Moses lived for forty years in self-imposed exile. It was in Midian that God appeared to Moses as the burning bush, telling him to go back to Egypt to free the Israelites.
The character played by David Cronenberg is named Dr. Philip K. Decker, a reference to sci-fi author Philip K. Dick. Deckard was the last name of the protagonist in Dick's "Do Androids Dream of Electric Sheep?", which was later adapted as Blade Runner (1982).
The role of Ohnaka was first intended for singer Marc Almond, and he was contracted to play the part, but his management strongly advised against the role given the nature of the film, as he was seeking to redefine his previously dark image as a more mainstream crooner at the time. The part subsequently went to Simon Bamford, who was already a friend of Clive Barker.
The song "Skin" by Oingo Boingo from the album "Dark at the End of the Tunnel" is playing on the radio (though not performed by Oingo Boingo) in the outdoor scene where Decker kills the woman he's picked up.