When Kinderman connects the murder victims in this film to the case in the first movie, it is revealed that one victim, the African American boy, is connected because it was his mother that determined that Reagan was speaking backward English. However, when you watch the first movie, the person that determines the language is a man that is Caucasian.
Kinderman clearly punches Patient X in the nose with his right hand (Patient X's left nostril begins to bleed, and his head rocks back to the right); yet later, Nurse Allerton bandages Kinderman's left hand (over the course of a protracted dialogue scene).
During the breakfast conversation between Father Dyer and the university president there is an old man heading very slowly for the buffet behind the university president. And after cut and reverse cut he disappeared completely.
The buildings depicted as being Georgetown University Hospital in the film occupy a block near the school's main campus. They actually housed the hospital from 1898 to 1930. However, after that, the hospital moved to a much larger campus a few blocks northwest. At the time of filming, the old hospital complex housed a variety of non-medical activities, and its internal geography bore no relation to the interiors depicted in the film. The hospital room where Kinderman views the blood vials is located, judging from its view, where a student apartment was in real life. The corridor outside the room would have run through a wall into an adjoining classroom building. The interior decor of the hospital is based on Georgetown's student center, which represented the hospital in some location shots.