Nicolas Cage playing Peter Loew ate a real cockroach for this film - it reportedly took three takes. He once said about the experience, "Every muscle in my body didn't want to do it, but I did it anyway."
Peter's strange accent is supposed to be a fake accent used by the character because he thinks he sounds more "elegant" and "smarter" (hence the literary agent job). The accent comes and goes throughout the movie and is more prominent when trying to impress people, and less in scenes with people like the psychiatrist.
With this movie and the earlier film The Bride (1985), actress Jennifer Beals achieved the distinction of having played both a Female Vampire and the Bride of Frankenstein. Both of the pictures were consecutive back-to-back films for Beals.
New York locations in the movie getting a special mention during the film's closing credits included The Tunnel; the Mondo Cane Blues Bar; the Man Ray Restaurant; Magickal Childe; the Apple Core Theater; the Circle-in-the-Square Theater and and The New Museum of Contemporary Art.