In 2009, the TV show MythBusters (2003) set out to prove the stunt where the Lamborghini skips across some water to escape the police. They proved that a stock Lamborghini could not do the stunt and that the car in the movie must have been specially weighted and that it was possible that the water was very shallow and the car may have actually landed on its wheels when skipping. In other words, "busted".
Burt Reynolds turned down a huge sum of money from Cannon Films to return for The Cannonball Run III, to focus on shedding his "good ole boy" image and becoming a serious actor. The film's title was subsequently recast and changed to Speed Zone.
John Schnieder of Dukes of Hazzard fame plays an unknown character of the driver of the Lambourghini in the opening get-away scene. His role is credited as Donnato, however he is not Donnato at all, the character heard on the phone in the police station. His character was never given a name and due to sloppy research by the credit team, was mistakenly named Donnato in the credits.
Many actors in this film appeared in SCTV. John Candy and Eugene Levy pulled a lot of favours to get fellow cast members and friends to appear in this movie. Rick Moranis turned down the role of Whitman.
The black Ferrari Daytona Spyder used in this film is actually one of the replica cars (based on a Corvette frame, transmission and engine) that appeared in seasons 1 and 2 (and a single episode in season 3) of the television show 'Miami Vice.' The car was further modified for this film (the Corvette door handles and rear quarter lights were moved, removed, etc.) to help make it appear even more like an original Ferrari .