| Bill Smitrovich | ... | Andrew 'Drew' Thacher (83 episodes, 1989-1993) |
 | Patti LuPone | ... | Elizabeth 'Libby' Thacher (83 episodes, 1989-1993) |
| Chris Burke | ... | Charles 'Corky' Thacher (83 episodes, 1989-1993) |
| Kellie Martin | ... | Rebecca 'Becca' Thacher (83 episodes, 1989-1993) |
| Tracey Needham | ... | Paige Thacher (40 episodes, 1990-1993) |
| Chad Lowe | ... | Jesse McKenna (35 episodes, 1991-1993) |
| Monique Lanier | ... | Paige Thacher (22 episodes, 1989-1990) |
| Tommy Puett | ... | Tyler Benchfield (15 episodes, 1989-1991) |
| Kiersten Warren | ... | Goodman (13 episodes, 1992-1993) |
| Penny Santon | ... | Teresa Giordano (12 episodes, 1990-1993) |
| Al Ruscio | ... | Sal Giordano (10 episodes, 1990-1992) |
| Troy Evans | ... | Artie McDonald (9 episodes, 1991-1993) |
| Andrea F. Friedman | ... | Amanda Swanson (9 episodes, 1992) |
| Michael A. Goorjian | ... | Ray Nelson (8 episodes, 1991-1993) |
| Dorothy Lyman | ... | Mary McKenna / ... (8 episodes, 1991-1993) |
| Michele Matheson | ... | Rhona Lieberman / ... (7 episodes, 1989-1991) |
| Gloria Gifford | ... | Mrs. Kneffer (7 episodes, 1989-1993) |
| Steve Jerro | ... | Paul / ... (7 episodes, 1990-1991) |
| Eric Welch | ... | Brian Russo (6 episodes, 1989-1991) |
| Lisa Zebro | ... | Mrs. Schiller / ... (6 episodes, 1989-1991) |
| Peter Van Norden | ... | Paintz Kutner / ... (6 episodes, 1990-1992) |
| John Welsh | ... | Eddie (6 episodes, 1990-1991) |
| Robert David Hall | ... | Mr. Mott (6 episodes, 1991-1993) |
| Christopher Graves | ... | Baby Nick (6 episodes, 1992-1993) |
| Kevin Graves | ... | Baby Nick (6 episodes, 1992-1993) |
| Steven Eckholdt | ... | Kenny Stollmark Jr. (6 episodes, 1992) |
| Lance Guest | ... | Michael Romanov (6 episodes, 1992) |
| Tanya Fenmore | ... | Maxie (5 episodes, 1989-1991) |
| Craig Hurley | ... | Kent / ... (5 episodes, 1989-1991) |
| Alfred Dennis | ... | Miller (5 episodes, 1990-1992) |
| Adam Carl | ... | Matt Hardy / ... (5 episodes, 1990-1991) |
| Elyssa Davalos | ... | Doreen Gillespie / ... (5 episodes, 1990-1991) |
| Gina Hecht | ... | Cousin Angela (5 episodes, 1990-1991) |
| Karen Rauch | ... | Lisa Galloway / ... (5 episodes, 1990-1991) |
| Barney Martin | ... | Stan Baker (5 episodes, 1991-1992) |
| Martin Milner | ... | Harris Cassidy / ... (5 episodes, 1992) |
| Drew Snyder | ... | Bill Swanson / ... (5 episodes, 1992) |
| Charlotte Stewart | ... | Mrs. Swanson / ... (5 episodes, 1992) |
| Ryan Bollman | ... | Lester / ... (4 episodes, 1989-1991) |
| Mike Marikian | ... | Brent / ... (4 episodes, 1989-1990) |
| David Byrd | ... | Hans (4 episodes, 1990-1993) |
| Alan Blumenfeld | ... | John Katchadorian / ... (4 episodes, 1990-1992) |
| Charles Frank | ... | Jack Benchfield (4 episodes, 1990-1992) |
| Judith Jones | ... | Kari (4 episodes, 1991-1992) |
| Mitzi McCall | ... | Midge (4 episodes, 1991-1992) |
| Whip Hubley | ... | Dr. Oliver Matthews / ... (3 episodes, 1989-1991) |
| Denis Arndt | ... | Earl / ... (3 episodes, 1989-1990) |
| Oliver Clark | ... | Mr. Leighton (3 episodes, 1989-1990) |
| Steve Eastin | ... | Scolassi / ... (3 episodes, 1989) |
| Kristin Pearcey | ... | Tiffany (3 episodes, 1989) |
| Fern Fitzgerald | ... | Robin Benchfield (3 episodes, 1990-1992) |
| Teri Ivens | ... | Janet / ... (3 episodes, 1990-1991) |
| John Ingle | ... | Father Holduin / ... (3 episodes, 1991-1993) |
| Michael Earl Reid | ... | Leo (3 episodes, 1991-1992) |
| Michael Alldredge | ... | Mr. Seedling (3 episodes, 1991) |
| Paula Marshall | ... | Jill Gordon (3 episodes, 1992) |
| Ned Vaughn | ... | Eric (3 episodes, 1992) |
| Judy Race | ... | Friend #2 / ... (2 episodes, 1989-1993) |
| Kaley Ward | ... | Art Patron #1 / ... (2 episodes, 1989-1992) |
| Parley Baer | ... | Mr. Hube (2 episodes, 1989-1990) |
| Adam G. | ... | Jim / ... (2 episodes, 1989-1990) |
| Don Maxwell | ... | Officer / ... (2 episodes, 1989-1990) |
| Mario Roccuzzo | ... | Tony (2 episodes, 1989-1990) |
| Matthew Ross | ... | Marty / ... (2 episodes, 1989-1990) |
| Scott Weinger | ... | Steve Smith (2 episodes, 1989-1990) |
| John Wheeler | ... | Announcer / ... (2 episodes, 1989-1990) |
| Kevin Telles | ... | Pederson (2 episodes, 1989) |
| Jordan Lund | ... | Henry Muckerman (2 episodes, 1990-1992) |
| Udana Power | ... | Kathy Gutman (2 episodes, 1990-1992) |
| Mary Page Keller | ... | Gina Giordano (2 episodes, 1990-1991) |
| Lisa Lawrence | ... | Julie / ... (2 episodes, 1990-1991) |
| Melora Marshall | ... | Mrs. Gilmore / ... (2 episodes, 1990-1991) |
| Leigh Ann Orsi | ... | Zoe Giordano (2 episodes, 1990-1991) |
| David Selburg | ... | Dave Gutman (2 episodes, 1990-1991) |
| Nancy Stephens | ... | Sharon Galloway (2 episodes, 1990-1991) |
| Nick Angotti | ... | Roy Hergenroeder (2 episodes, 1990) |
| Stephanie Dicker | ... | Shelley (2 episodes, 1990) |
| Billy Gallo | ... | A.J. Salcedo / ... (2 episodes, 1990) |
| Seth Green | ... | William Butler (2 episodes, 1990) |
| Paul Koslo | ... | Farmer Jack (2 episodes, 1990) |
| Heather Lind | ... | Young Becca (2 episodes, 1990) |
| Susan Merson | ... | Lucy (2 episodes, 1990) |
| Lynn Milgrim | ... | Dr. Tabouri (2 episodes, 1990) |
| Joe Stark | ... | Max / ... (2 episodes, 1990) |
| Susan Varon | ... | Customer #2 / ... (2 episodes, 1990) |
| John Apicella | ... | Dr. Rosenfeld / ... (2 episodes, 1991-1992) |
| Frances Bay | ... | Eleanor / ... (2 episodes, 1991-1992) |
| Bodhi Elfman | ... | Mark (2 episodes, 1991) |
| Bradley Mott | ... | Mr. Sommers (2 episodes, 1991) |
| Juanita Jennings | ... | Detective Davis (2 episodes, 1992-1993) |
| Peter White | ... | Kenny Stollmark, Sr. (2 episodes, 1992) |
| Tim Eyster | ... | Tommy (1 episode, 1989-1991) |
