This movie was filmed at the same time as two other John Hughes movies: The Great Outdoors (1988), which was written by Hughes, and Planes, Trains & Automobiles (1987), which was written and directed by him. Some of the same cast members from both films appear in this film in cameos seen at the end of the picture.
Paul Gleason plays an uncredited character called "Blind Boy Grunt". Blind Boy Grunt was a pseudonym used by Bob Dylan in the early 1960s, and was also the name of a famous bootleg album of his in the early 1970s.
The hospital where Kristy has the baby, The Evanston Hospital, is a real hospital located in Evanston, Illinois. It still exists today (as of 2016), but has been extensively remodeled to the point of not looking like the hospital in the film. It is also now called the Northshore Evanston Hospital.
The teaser trailer appeared on the January 1987 video release of Ferris Bueller's Day Off (1986), but the film was not released until over a year later, due to John Hughes having problems editing the film during post-production.
Kevin Bacon later top-billed He Said, She Said (1991) for Paramount Pictures, having previously headlined the earlier 1980s box-office hit for the studio, Footloose (1984). Bacon had also appeared in other 1980s Paramount films, such as She's Having a Baby (1988) and Planes, Trains & Automobiles (1987).