Hanson goes undercover at a rough school after a drug dealer is found shot to death in the parking lot. Penhall dons a uniform and patrols with a veteran officer that works in the community. Hoffs tries to help a junkie involved in the case.
With Fuller's help, Penhall tries to prove that Adabo pushed the drug dealer from the roof, and Hanson replaces him on the beat with Adabo. Meanwhile, Hoffs tries to help Darlene get clean. Also, Hoffs and Penhall turn to each other for help with their problems.
Following an increase in drunk driver accidents involving teens Hanson and Penhall investigate the source providing fake identifications to underage drinkers. Meanwhile, Captain Fuller gets busted for DUI.
Hanson and Hoffs go undercover in a school with a new black principal and a recently integrated student body to investigate escalating racial tension between white and black students. Meanwhile, Penhall aspires to be a stand-up comedian.
Hanson and Penhall work as body guards protecting a popular young actor that has received threatening letters. Drug dealer Tyrell "Waxer" Thompson escapes from prison and goes after Hanson for revenge.
Hoffs works a drug case by going undercover and becoming the dealer's girlfriend, but she gets a little too close. On the same case, Penhall and Ioki go into a school posing as "twins" who want to help ship the drugs.
Hanson investigates a series of bathroom bombings in the final case of the school year. The Jump Street Program is suspended for the summer. The team disperses to summer jobs knowing that it may not be renewed in the fall.