Throughout the entire series run, the closing credits have never credited Paul Reubens as Peewee Herman, but instead would display the other cast & guest stars first and then would display "and Peewee Herman as Himself".
It is often assumed that the main reason for the cancellation of the series was Paul Reubens indictment for obscenity for an incident in an adult theater in Florida, but in fact Reubens and CBS had mutually agreed to end the show in 1991. CBS did, however, choose not to air the reruns of episodes they had planned for August of that year, and the final network telecast was 27 July 1991.
Only two episodes, plus the Christmas at Pee Wee's Playhouse (1988), were created for the third season, due to both Paul Reubens working on Big Top Pee-wee (1988) and production being halted by the strike caused by the Writers Guild of America in 1988. John Paragon wrote both episodes for this season, and together with Reubens, wrote the Christmas special.
Several notable changes to the show's characters, cast, or set occurred over the years. At the start of season two, the show moved from its New York City warehouse studio to facilities at the Hollywood Center Studios, creating changes in personnel and a change to the set that allowed the show to take advantage of the additional space.
During the first season's opening credits, Pee Wee is seen spinning in front of a large picture board. One picture is a drawing of J.R. "Bob" Dobbs; figurehead of the satirical Church of the Subgenius.