It's George's birthday. He's been pushing Wesley to excel at baseball and when Wesley decides to cheat, George is upset at him and Wesley say she did it for him. When they throw him a party, and help George relive some of life's greatest moments but only shows him at how he has done nothing he set out to do, like play baseball with some greats. So Belvedere decides to give George a different present. The next day at Wesley's game, he arranged for some great players like Hank Aaron, Willy Mays, Reggie Jackson, Johnny Bench, and Ernie Banks to be there. and along with ...
Belvedere gets George to invest in live commodities, pigs. While Belvedere sells out, George holds on to it without knowing that if he doesn't sell them, he will have to take possession of them. So dozens of pigs are sent to him. So he has to unload them. And the only buyer is out of town. So he hires a truck and he and Belvedere set out to deliver them. Eventually they like being truckers and decide to do it leaving Marsha and the kids.
George and Marsha are planning a trip but when George learns that they have to fly to get there, he backs down. When Belvedere learns that George has a fear of flying he does what he can to help. He takes George to the amusement park and they both go on the Ferris wheel. However, when they get stuck George's fear increases. Belevedere then enrolls George in a fear of flying therapy group.
When a woman claims that Wesley's dog is harassing hers and worried that he might impregnate her dog which she plans to breed. They instruct Wesley to have his dog fixed which he tells him they did. But when the woman returns with puppies she claims were sired by Wesley's dog, Wesley has to find homes for them.
When the owner of Belvedere's favorite Donut shop dies and leaves the donut shop to him, it upsets Lou Anne, the employee who thought she's getting it. So she quits. When Belvedere spends too much time at the donut shop, the Owens hire Lou Anne to help out.
Mrs. Checchini comes to Belverdere begging for his help. It seems like her family wants to put her in a home. Belvedere doesn't do anything. And when he goes to visit her, he finds her with no spark as she usually does.
Louise and Mr. Belvedere decide to get married, but Louise soon breaks the news to him that she has been called to go back Africa, and wants him to come with her. He agrees, but not without a final goodbye from old friends Skip, Angela, Robert Goulet, and of course, the Owens family, who have enjoyed six years of his company.