A homeless boy wishes that someone would love him and so Jonathan comes to him and offers to make his wish come true. They go to a man whose separated from his wife who refuses to let her see their son. And he also refuses to believe that his son who's confined to a wheelchair is because of something psychological.
Jonathan and Mark emerge from a meteor crater to offer extraterrestrial encouragement to Adam, a young, bullied orphan whose eccentric grandfather is in danger of losing him to a heartless social worker.
While working for Linda Blackwell, a beautiful movie star with a very low opinion of men, Mark and Linda both wish "to God" that each could have the other's life ... with the result that "The Boss" takes them at their word and switches Mark and Linda into each other's bodies.
Jonathan and Mark help a whole town to remember how a young soldier who was killed in Vietnam touched their lives when the attempts of his father to have a memorial made to commemorate his son are ignored.
Mark becomes deeply stricken with grief after believing he caused two tragedies involving young girls - one of them a victim of a car accident, the other trapped in a house fire - in a matter of hours. That, along with a litany of other complaints, prompts Mark to make a demand: That Jonathan erase everything that's happened and allow him to create his own vision of "Heaven on Earth."
Mark and Jonathan try to reunite a mother with her son who is now the Deputy Premier of the U.S.S.R. When he is told that his mom would like to see him he believes Jonathan is with the CIA and not an angel.
A home for unwed mothers is endangered when a sensationalist reporter uncovers a secret about the past of the woman who runs the home, and a teenage boy must come to terms with the fact that he's a father.
Jonathan and Mark are substitute teachers in a high school where a lesson on true friendship is underscored by Jonathan's assigning an ostracized overweight girl to tutor a brash baseball star in danger of flunking out of school.
Jonathan and Mark persuade a youngster with Down's Syndrome to join the Special Olympics. Coached by his older brother and, because of their parents' keeping the mentally handicapped child a secret, doesn't even know of the boy's existence. At the same time they try to help their friends Scotty and Diane, who can't have children.
Scotty and Diane want to and are determined to adopt Todd, but Todd's parents won't agree and both sides are prepared to fight it out in court with both Todd and his older brother caught in the middle.
Bill Cassidy is a model TV dad of the hit series, "That's Our Dad, a show known for its closing (where he "adopts" two orphaned children at the end of each show). At least on-screen Cassidy is the model TV dad. Off the set is a little different story. Bill is an egotistical jerk who verbally abuses his co-stars and crewmembers ... and even the children he was said to have adopted. His off-screen attitude is put to the test when two orphans, who happen to be fans of "That's Our Dad," and especially Bill Cassidy. The two track down Bill and ask if he'd consider adopting...
Jonathan and Mark are on their way to their next assignment and meet another angel, Ted, whom Jonathan knows, and they both arrive at their destination. When Ted learns that the subject of his mission is his wife Laura and that it involves pairing her with a guy named Roy, not only does he refuse to do it, but he sabotages any chances Roy may have had with her. He then romances her himself but Jonathan steps in and shows what damage he has done and so to fix, he starts acting like a jerk which inspires Roy to tell him to leave Laura alone and their romance begins.
Mark's invited to attend the wedding of a friend. Mark is keen on his friend because he and his wife have a rock solid marriage. As does his parents. But upon arriving parents have a little spat that ends with them parting ways. And Mark's friend and his wife decide they need a break. And their daughter decides she doesn't want to get married because of what happened. So Jonathan and Mark try to help them.
Jonathan is working as a teacher at a college. And the focus of his assignment is a young boy genius who's accepted to college. The boy feels like an outcast. His roommate is a guy who's on an athletic scholarship. When his roommate has trouble in a class, he's asked to help get him a copy of a test. But when it's found out what happened, things get out of hand.
Jonathan and Mark try to get a father and son to get to know each other again before Gary loses his father due to leukemia. Jonathan tries to make these tycoons live life to the fullest and not work so hard.
Jonathan persuades an influential United States senator to restore severe Congressional budget cuts dealing with health-care, but when the senator suffers a fatal heart attack on the Senate floor, the assignment seems doomed to failure.
It's Christmas and Jonathan and Mark's assignment is try to show a columnist named Basinger, who's become cynical, that there's still some good out there. They learn of a young couple named Joseph and Mary who are expecting their first child but can't find a place to stay. They take them to the hospital and along the way they pick up another couple who are also about to have their baby. And when they get there, the hospital refuses to admit Joseph and Mary but the wife demands that they let them in or else Basinger will write about it.