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Several affairs (both pre-marital and extra-marital) are major plot-points in the film. These are discussed frankly but without explicit discussions of sexual acts.A man offends a woman by caressing her breast under her dress.
A man falls down drunk and hits his head on the curb; he scrapes his brow causing bleeding.A woman slaps her grandson in the face several times.
The F-word is used twice and the S-word three times along with other milder profanitiesThe coarse language in this movie is not frequent.
Friends smoke pot near the begening of the film. Several characters drink, sometimes to drunkenness, in a few scenes. This is played for laughs.
There are some very potentially and disturbing scenes where cancer plays a major role. One person does succumb to her illness.