The end of the film promises "Doctor Detroit II, the Wrath of Mom" which was in the works. In fact, Dan Aykroyd was writing the script. But when this film turned out to be a box office bomb, Universal pulled the plug.
Fran Drescher has said in her autobiography "Enter Whining" that the movie was expected to be a box-office hit, but it wasn't, by the time the film finished its run it had only made US $ 10.8 million from its budget outlay of US $ 8 million.
Skridlow's poetic recitation at the trunk of his car is mostly an excerpt from William Shakespeare's "The Life of King Henry The Fifth" (Act IV, Chorus). However, he misquotes the first phrase, saying "From inside the jouster's tents . . .", which is not from any of Shakespeare's writings.
Arthur Skridlow bemoans at one point "when you have a woman mayor". Jane Byrne (born May 24, 1934) was the first and (to date) only female Mayor of Chicago. She served from April 16, 1979 to April 29, 1983. Chicago is the largest city in the United States to have had a female mayor as of 2012.
Although listed by character name in the credits as Miss Debbylike and shown rather prominently in the classroom scene (seated behind Peter Aykroyd, directly in the shot), Glenne Headly has no speaking part in the movie.
The academic discipline that Clifford Skridlow was a professor of was comparative literature. The name of the university he taught at was Monroe College. The distance he power walked to work every day was six miles.
T.K Carter has starred in movies with Dan Aykroyd and Chevy Chase who are friends in real life, Carter starred with Chevy Chaee in (seems like old times 1980) and (Dr Detroit 1983) coincidentally in both movies Carter plays a chauffeur and butler.