St. Eligius is reopened thanks to a new corporate owner, whose plans please Craig but leave Westphall wondering; Elliot is missing from the returnees; Fiscus finds the first patients; the Craigs' marriage seems to be headed for court.
A student nurse's lie comes back to haunt her; Warren wants better conditions for the orderlies; Craig's artificial-heart program improves as his marriage deteriorates; Wade's hostelry is filled with hostility.
Plans change for the Craig 9000; Rosenthal returns to the OR; Morrison's real life clashes with his new public image; a "bashing" incident leads to an understanding between Griffin and Brett Johnson; Ellen and Craig start an affair.
The artificial-hear press refuses to speak to the press; Auschlander wonders about his last days on Earth; Fiscus visits his father during his suspension; sparks fly between Novino and a man called Pee Wee.
Craig and Gideon are both affected by death; Ehrlich is too busy with his work to spend time with Papandrao; Rosenthal feels pressure under visual scrutiny; Luther shares his thoughts on size with a big man.
Ehrlich verbally assaults Craig; Griffin fails as a spiritual counselor; Elliot undergoes surgery; Rosenthal enters family therapy with little support; Gideon is made the victim of another high-tech innovation.
A fire starts at the Doctor of the Year dinner; Papandrao and her in-laws look for Ehrlich; Chandler is in for a surprise; Fiscus tries to figure out how to tell his plans to his mother; Wade is upset by her patient's bickering parents.
Third-year surgeons end their residencies; Auschlander tries to keep the hospital open; Griffin places his trust in God; Ehrlich comes back from a soul-searching safari; Ellen is offered a job in Cleveland.