The Comic Strip Presents... The Red Top! - a working title - will star Maxine Peake as the infamous former tabloid editor, alongside Nigel Planer as Rupert Murdoch and Russell Tovey as Andy Coulson.
The show is described as the story of Rebekah, "an innocent and beguiling Northern girl" who through a series of accidental circumstances becomes Chief Executive of News International and gets tied up in a "'70s Watergate-style scandal".
A 75-minute "comic fantasy", the show follows in the footsteps of The Comic Strip's The Hunt for Tony Blair and will see Stephen Mangan reprise his role as the former Labour Prime Minister.
The new special will also star Johnny Vegas, Alexei Sayle, Harry Enfield and John Sessions.
Peter Richardson, who is behind the programme, said: "Like