Having just missed catching Baron Greenback in Tokyo, Dangermouse gets hold of the villain's digital hideout locater (disguised as a book). Using this device, DM and Penfold take a tour of the Baron's various hideouts hidden all around the world.
Greenback has persuaded Count Duckula to visit London. Desperate for a TV show of his own, Duckula infects the entire government with his own showbiz sickness so they will agree to his every demand. After capturing Danger Mouse and Penfold, the evil vampire duck subjects them to the absolute worst comedy variety show ever to grace a theater stage. Despite of this, Duckula somehow managed to get his own cartoon series before the decade was over.
A Demon from the Fourth Dimension appears on Danger Mouse's doorstep to challenge the one-eyed white wonder to a duel. Before they can duke it out on the Demon's home turf however, the world's greatest secret agent is sidetracked or rather suckered into his own TV spectacular: 'This Was Your Life'.
Proffesor Von Squakenkluck has invented a time machine and accidentally sends Penfold back 150 Million Years into the past in place of a dinosaur egg. Danger Mouse follows in the Mark 12, after changing places with a Diplodocus.
DM and Penfold have just retrieved a stolen secret fuel sample from Field Marchall Rommole. On their way back, the Mark 5 gets hit by an electric storm, Penfold is struck dumb and the two of them are shot into a distant future where Britain cats are the dominant species. Worse still, a distant relative of Baron Greenback rules the cats under the name of 'Big Leo'.
Colonel K has had his people create robot duplicates of Dangermouse and Penfold, so he can team the actual DM with robot Penfold and vice versa, in order to be able to stop more crime at the same time. The real Dangermouse and the fake Penfold are send to meet master of disguise Agent 57 at the Pinball Palace, where arch villain Baron Greenback is hatching a scheme to hypnotize the world by way of pinball machines.
While climbing the rock of Gibraltar, Dangermouse and Penfold spot Baron GB's Frog Head Flyer and follow it to New York. There, they enter the International Oddbods Inc, an agency which represents some of the world's greatest crack-pots.
Baron Greenback and Count Duckula have teamed up in a quest to find the Great Bone Idol, which has the power to control every dog in the world. Greenback plans to use it to take over the world and Duckula would get Australia. This is besides the fact that Duckula has to do all the work. DM and Penfold head for the Himalaya's to stop the villainous duck.
Just when he's infiltrated Baron Greenbacks secret hideout, Dangermouse loses his memory after a crash on the head. GB takes advantage of the situation by making DM believe he is the second greatest criminal mastermind in the world, the White Shadow. In this new guise, DM immediately goes off on a relentless crime spree, stealing from the rich and giving to the poor.