The house used for exterior shots in the opening sequence as well as various points throughout the show's run is 171-173 Buena Vista St, San Francisco, California. One episode in particular shows Monroe pulling out of the garage of this home on his motorcycle, another episode shows Norman giving directions to the house over the phone and offering correct bearings.
In one episode, Ted Knight wore a sweatshirt with the name and logo of an actual university on it. Soon, college and university students, who were fans of the show, began sending logo sweatshirts for Knight to wear on the air. From then on, Knight began wearing as many different sweatshirts as possible in each episode to please the fans.
After being canceled by ABC, the series aired in first run syndication. The original syndicated episodes were produced by Metro Media, and aired largely by Metro Media's owned and operated stations. This was an attempt by Metro Media to help develop a fourth commercial TV network, and helped pave the way for the FOX TV Network.