Divine was intended to play the role of Mole McHenry (played by Susan Lowe), but he was in a play for which he had a long-term contract, making him unavailable. David Lochary was also intended to act in the film, but he bled to death after falling on a glass while under the influence of PCP.
While most viewers recognize the portraits of Charles Manson and Adolf Hitler in Queen Carlotta's "art gallery", many are confused by the appearance of a heavyset black man in a military uniform. This is former Ugandan dictator Idi Amin.
Actress Susan Lowe who played "Mole McHenry" in the movie is actually very beautiful. After changing her appearance to play the part, her children were horrified, and it caused problems with her marriage.
John Waters: [manson] There is a portrait of Charles Manson in Queen Carlotta's cardboard castle. Also, someone in Mortville cries out "Squeaky Fromme, where are you when we need you?" Lynette Fromme, aka "Squeaky", was a Manson follower who tried to assassinate US President 'Gerald Ford'.