When a high school student drops dead at basketball practice, Quincy is drawn into an investigation in the dangers of "pep" pills and legal lookalike drugs and the problems in regulating the sales of such items.
When a baby with Down Syndrome is denied medical care after birth and allowed to starve to death, Quincy must determine if the death was from natural causes or if the attending physician had a different agenda.
After a former Vietnam nurse suffering from PTSD turns up dead, Quincy gets involved with a veteran support group in an effort to get the victim's friend, another former nurse, the treatment she needs for her disorder.
Quincy must aggressively go against a highly qualified colleague who is trying to prove that an acquaintance of his is guilty of murdering his infant son who is afflicted with Sturge-Weber Syndrome. Quincy is convinced of his innocence, but it will be tough to prove.
Quincy must unravel the mystery of who murdered the town bully in a small community outside of Los Angeles. He runs into opposition in this tight knit community who want to protect the killer, including local law enforcement.
When a cancer patient who's undergoing a new treatment leaves the hospital and dies, it is believed that she succumbed to the cancer. But when some people whom she came into contact with also die, it is believed that the treatment mutated into a virulent disease. So the doctor who's the one created the treatment is told by his boss, his work is over. So he goes to work for a pharmaceutical company who's only interest is in making money. And when another person becomes ill, Quincy implores the doctor to try and develop a cure.
Michael Morishima, a good friend of Sam's, is murdered in the Little Tokyo section of Los Angeles. It turns out that he was investigating possible Yakuza activity in Los Angeles. Unfortunately, Michael's old fashioned father now wants revenge. Now Sam and Quince must find the old man before he becomes a victim himself.