Quincy's hot temper and tenseness leads him to be sent to a small town, to get away from the stress of the city, working in the capacity of the town doctor. On his first night in town, he stumbles across what appears to be a fatal drunk driving accident. What he discovers is sloppy autopsy work and lackadaisical procedures from the town's police chief, doctor, and mortician, leading him to reopen the case so that the victim's widow will receive life insurance benefits.
While returning from a coroners convention, Quincy and Sam find a human skull in the desert. They immediately hire a forensic artist to use it to try to identify it. Eventually, they discover that the skull belonged to a missing labor leader. Soon, his main rival finds out and he and his goons threaten to stop Quincy by hurting the artist as well as Astin. Also, as the investigation goes on, Quincy discovers a hidden secret the man had that may have been the reason for his killing.
A teenager with a record is accused of murdering an elderly man. The teen happened to belong to a group run by Quincy's friend, former pro-football great Rosie Grier. Rosie asks Quincy not only to help clear the teen, but to help save the organization he runs, Giant Step, which helps to bring teens and the elderly together.
A young woman dies suddenly at a bar, and Quincy's autopsy shows her death was a result of a heart condition. However, Quincy doesn't believe the woman's husband is as devastated by her death as he should be, and becomes suspicious of his behavior. Further investigation leads him to the sister of a former wife, who also died before her time. The man is preparing to marry a third woman, and move to Brazil to avoid being extradited back to the US. Can Quincy find the true cause of death before the suspect leaves the country?
Nothing is adding up for Quincy in this episode. A prominent CEO is found apparently murdered in his office, and a suspect with a motive is in custody. However, the autopsy is uncovering some very strange test results, and every lead that Quincy follows seems to happen 9 years in the past. Quincy eventually is able to tie things together, and discovers an extensive murder plot that was 9 years in the making.
Quincy has doubts about Dr. Asten's findings in an autopsy that he performed on a man who died in a nightclub fire. Asten believes that the man is a victim of a homicide, while Quincy believes it could be natural causes.
Quincy and Sam are on their way to their weekly poker game with Astin, Monahan, Brill, Ed and Danny when they are accosted by a prominent mob boss who only has 24 hours to live. He suspects he was poisoned by his rivals and orders Quincy to perform an autopsy on him while he is still living and to find out where he was poisoned. If Quincy refuses, he and Sam will be killed.
Quincy and his girlfriend Barbara are driving up the coast on vacation when they are nearly run off the road by a young woman who is driving very erratically. She drives off the road and when Quince arrives at the wreck he discovers that she is dead. When Quincy performs the autopsy on her, he discovers that she died as a result of internal bleeding despite the fact that the wreck wasn't that serious. The next day, a police officer, who was inspecting the car, dies of apparently the same thing the woman did. However, things really become personal for Quincy when Sam ...
A race car driver is killed in a fiery crash. However, Quincy suspects foul play, especially when he finds amphetamines in the driver's system. He then tries to prove that it was murder while at the same time dealing with a nosy insurance investigator whose company had a major policy on the driver.
A young boy who has run away from a home for mentally handicapped children is found dead. When Quincy performs the autopsy, however, he can find no medical reason for the boy being labeled mentally handicapped. He consults with an expert who suggests the boy may have been autistic instead. Quincy learns of another boy who is about to be committed to the same institution who may also be autistic, and fights to have him properly diagnosed before time runs out to get him into a proper school instead.
When a patient at a hospital dies unexpectedly, the (black) doctor who was taking care of him is being questioned as to if he gave the patient the proper care. And also it seems that the doctor got his job cause of an affirmative action program, and if he did do something wrong, the whole program is in jeopardy. The man who spearheaded the program who is a friend of Quincy's offers to take the fall but it will cost him his job. So Quincy tries to prove the doctor didn't do anything wrong.
The world's most successful female television journalist appears to have been killed in a motel fire. But when the woman walks into the press conference where Quincy is announcing the cause of her death, people begin to question Quincy's competence. He has dental and x-ray evidence that support his findings, but when he starts hounding the journalist, trying to figure out who she really is, his career is in jeopardy.
Quincy is called in to investigate the shooting of a bar owner in an apparent robbery attempt. During the investigation, the suspect panics and grabs the gun he used in the course of the robbery and starts shooting. During the shooting, Quincy is shot and is in grave condition. Monahan, Sam and Astin try to piece together what happened and using their memories of past cases that Quince worked on they try to figure out if he was shot by accident or maybe that his shooting was deliberate.
After a courier van crashes into a gas station, Quincy declares that the driver died. But when the victim's sister starts getting odd calls that sound like they're coming from the dead man, Quincy decides that the driver was blown clear of the crash and is now wandering around somewhere, injured and disoriented. The courier company owner and the "dead" man's mother, however, support the initial determination. They want further investigation shut down, and it's up to Quincy to find out why, and more importantly, to find the driver before he dies for real.
Quincy helps his girlfriend move into a very odd rooming house. On her first night, however, she discovers two bodies mummified and hidden in the attic. Soon two more bodies are discovered, which confuses the person who put three of them there. Quincy determines that the fourth body is a murder victim, but who was the murderer and how the person died isn't clear yet.
During a severe rainstorm, a mudslide washes several caskets from an old and supposedly abandoned cemetery. At first things look routine as Quincy tries to identify the bodies. However, he discovers a recently deceased man among the corpses and even worse the body shows signs of typhoid. Unfortunately, when Quincy tries to see if anymore bodies are buried up there his efforts are blocked by a senatorial candidate who had a stake in the cemetery. Now Quince must try to cut through the red tape to not only find any more bodies, but to try to prevent a full scale ...