When a wealthy winegrower disappears, the three private investigators go undercover at the vineyard to track down the whereabouts of the body. If the body doesn't turn up in a certain amount of time, the inheritance will be presented to the man's second wife, Rachel, instead of his long-lost daughter, Janet.
An investigation to determine whether sabotage was behind the death of a race car driver finds Sabrina behind the wheel in a dangerous, high stakes race, Jill and Bosley posing as traveling preachers and Kelly getting in good with their lead suspect.
The Angels head to Mexico to infiltrate a heroin smuggling ring & unearth the identity of a mysterious smuggler known as Escobar; Sabrina poses as a stewardess, Jill as a swimming coach and Kelly as a vacationing schoolmarm.
Dana Cameron, a fashion model who bears an uncanny resemblance to Kelly, falls victim to the so called 'Rag-doll Strangler'. Kelly and Jill join the St. Clair Model Agency and Sabrina cons herself into a job as a photo stylist. Each time they think they suspect someone of being the killer, the strangler strikes again, leaving the suspect with an alibi (usually one of the Angels themselves).
The Angels are hired by a young woman to find out what happened to her sister who was an inmate at a women's prison. They decide to go undercover at the prison to find out what happened to her and they eventually find out that the local sheriff who runs the prison has been forcing the inmates into prostitution.
A series of attempts on the Angels' lives lead them to seek refuge in Charles Townsend's palatial home (where Bosley has already removed any evidence of Charlie's appearance). However, the three girls discover just in time to save their boss's life that he is the true target - allowing Charlie to once again slip away into obscurity.
The Angels investigate the death of a young reporter named Brooke Anderson, who had written a manuscript containing evidence of a major scandal going on at the Moonshadow resort. Jill poses as a tennis instructor, Kelly a fashion photographer and Sabrina as a fashion designer. Bosley is supposed to be her model, only his wife packed the wrong kind of shoes to go with his tux.
A young autistic boy named Skip that Kelly has been acting as a volunteer big sister to finds a gun and accidentally shoots her with it. He then panics and runs away. Sabrina and Jill try to find the boy, who is collecting various items that he thinks will awaken Kelly. Also on the boy's trail are a pair of killers who think that Skip might have witnessed their crime.
Two Centerfolds from Tony Mann's Feline Club have been killed, so the Angels are called in to investigate. Jill draws the short straw (or pencil to be more precise) and gets to be a Feline cocktail waitress. Kelly joins the club as a singer (although she does in fact lip-sync) while Sabrina poses as Mann's latest flame (even though he usually only dates women under twenty).
After incurring pressure from her insurance agency, wealthy widow Grace Rodeheaver hires the Angels to investigate her case of jewelry missing, and upon discovering that she consults with a medium to handle her affairs, Kelly unwittingly offers damning information.
After Roller Derby champ Karen Jason is killed in a competition, her sister Barbara hires the Angels to investigate, believing the death was intentional. The girls go undercover as a journalist, insurance investigator & a team member.