Due to threats on her life, Starsky and Hutch are assigned to protect a visiting Russian ballerina. Hutch, a big fan, is impressed by her talent, but disappointed with her bristling personality as they get off on the wrong foot.
A weekend trip to Captain Dobey's cabin turns sinister for Starsky & Hutch when they discover a cult across the lake and try to determine why the sheriff and inhabitants of the nearby small town are treating them so strangely.
During a high-speed chase, Starsky's reckless driving lands the partners in the hospital, where Hutch appears to be stricken with amnesia. Starsky attempts to revive Hutch's memory by reminding him of their past adventures.
A serial killer who preys on prostitutes is wounded during his latest attack. When he takes Hutch's friend and her invalid mother hostage in their home, Hutch poses as a paramedic to get inside the house.
After the duo fail to capture a wanted felon, Hutch bets that he can successfully elude Starsky for 48 hours. The game becomes deadly serious when Starsky discovers that Hutch has unknowingly eaten soup contaminated with botulism.
Starsky unknowingly places himself in serious danger when the Detectives investigate a woman's claims that a jealous ex-lover from San Francisco has followed her and is responsible for the murders of her recent one-night stands.
A top model believes she has terminal cancer and arranges for a genius hit-man to end her life. She discovers the cancer is in remission, but it is too late to cancel the contract, so she turns to old flame Hutch to prevent her own death.
Starsky's little brother, a smalltime hustler, arrives in town to visit Starsky. He's approached by the mob and he thinks he's become a big fish until he gets caught up in a net he can't get out of without Starsky's help.