With a young daughter and a job offer waiting in Japan, times should be happy for Lionel and Jenny Jefferson. But they're far from happy; in fact, they're so happy they've agreed to a separation. This sets none to well with the Jeffersons or the Willises, who are determined to get at the root of the matter ... or in George's case, meddle to the point where they have to get back together.
A newspaper article reveals that a man with the same name as Louise's father thwarted a crime. Since the man's picture and name are similar to those of Louise's presumed-dead father, George investigates.
George feels down due to a mid-life crisis, so Louise tries to cheer him up by sending him flowers with a seductive anonymous note attached. George concludes that his bookkeeper Carol sent the flowers and is in love with him.
A near-death experience prompts George to work toward ensuring that his life and work inspire others, so he decides to write his autobiography - until a casual remark from Tom Willis gives him an even more pompous idea.
New neighbor Sammy Gilson the songwriter is upset and creatively blocked due to marital woes, so George tries to cheer him up but has an ulterior motive: he wants Sammy to write a winning publicity jingle for Jefferson Cleaners.
One of George's stores in Brooklyn catches fire and is heavily damaged. When faulty wiring is suspected, Tom encourages him to file an insurance claim and hold the man responsible for the bad wiring. Bad news: Lionel installed the wiring!
Lionel and Jenny's apartment is burglarized and looted. George worries that the crime wave will spread to his "deluxe apartment in the sky" and is determined to buy some insurance ... in the form of a gun. Louise totally objects, and is outraged when George goes behind her back to buy one. George finally realizes that a gun is a dangerous investment when little Jessica accidentally fires it and barely avoids shooting herself.
The Jeffersons' and Willises plan a surprise party for Florence, but their cover story hurts her feelings so badly that she skips the event and commiserates with Ralph over their mutual lowly-servant status.
One of the delivery boys at Jefferson Cleaners is robbed at gunpoint by a street gang ... made up entirely of female hoods. When George goes to confront the female gangsters, they easily subdue him and then stab him. While he is writhing in pain on the sidewalk, the girls help themselves to Louise's ring George was taking to have reset as an anniversary gift.
It turns out that George is OK and will recover, but while recuperating, he contemplates a plan to get Louise's ring back from The Strays (the all-female gang whose members nearly killed George), despite her objections. George decides to hatch his plan for revenge anyway, knowing full well that the consequences could be far more severe.
A record company talent scout hears Florence sing in church and offers her a chance to cut an album. But George gets suspicious and thinks the man is nothing but a common swindler out to take Florence's $1200 life savings.
The cast plays in a Western spoof, with Florence as a waitress, Ralph an undertaker, George a gunslinger, and Louise a help counter proprietress. Tom is a bumbling cuckold who faces an outlaw that has come to steal brazen adulteress Helen.