George and the others anxiously wait for the telephone call from the crooks who claimed they have kidnapped Louise, until she walks right into the apartment unscathed. Louise insists she never knew anything about kidnappers, and while everyone breathes a sigh of relief, there's one more question: Where is Florence?
George is excited when he learns that an old Navy pal is in town and wants him to stop by at his hotel for a visit. However his old pal, Eddie, has a big surprise for George; his name is now Edie and he has undergone a sex change operation. Meanwhile, confusion with Eddie's name leads Louise to believe that George is having an affair with a woman named Edie.
Louise is hoping that Fay Blanchard, the director of the Neighborhood Help Center, will appoint her as editor of the center's newsletter. However, when Fay meets Helen and is impressed with her credentials, she gives Helen the job instead.
Marcus meets customer Natalie Parker at Jefferson's Cleaners and tells her he is George's son so she would date him. However, when Natalie meets George and tells him she is dating his son, George thinks Lionel is having an affair.
When the lease on the Jeffersons' apartment is going to expire, H.L. Whittendale is thinking about renting the apartment to close friends of his. Worried about losing their home, George and Louise invite Mr. Whittendale over for a drink and social hour, hoping to gain his friendship. However, the man they invited over turns out to be H.L.'s brother, R.S. Whittendale.
When Lionel gets laid off from his job, George hires him to work in his office. However, Lionel turns out to be trouble when he started spending company money on material things like new furniture and employee blazers.
As a publicity gimmick for his store, George tries to get President Carter to stay with him. After a phone call to the White House degenerates into an argument, George's comments are interpreted by the Secret Service as a threat to the President.
A burglar breaks into the Jeffersons' apartment and ties up George and Louise. As the burglar goes about his work, the couple are left to reminisce about their past. This episode includes clips from both "The Jeffersons" and "All in the Family."