John, Liz and Stephen sense the breakout of a new Tomorrow Person, Tyso Boswell. Unknown to them, however, he has already come to the attention of Professor Cawston, who introduces him to the mysterious Colonel Masters.
The Tomorrow People are visited by Timus, an ambassador from the Galactic Federation. He tells them of the planet Pyrie, where telepaths are oppressed by the servants of the alien Khultan, and asks them to go there to help them.
The Tomorrow People meet up with Tikno, the clone brother of Timus who is on Pyrie for the same reason as them. He takes John and Stephen to meet the local telepaths, the Vesh, to try and persuade them to join forces.
Liz, Tyso and Lenda have been captured by the Veshtakers and sentenced to burning. While Stephen and Arkron try to rescue them, John, Tikno and the Vesh infiltrate the Khultan's pyramid in an attempt to restore everyone's powers.
A group of aliens stop off on Earth for supplies, but since their only knowledge of Earth's culture comes from watching cowboy films, it is not long before their visit results in violence and the Tomorrow People become involved.
When one of his colleagues goes missing after an expedition to Egypt, Professor Cawston goes to the Tomorrow People for help. They soon realise the expedition unearthed Jedikiah, who is attempting to track them down.
John and Liz are on life support at the EWE. Their only hope of recovery lies with Stephen and Tyso, but Cawston refuses to let the boys near them, afraid one of them might be the shape-shifting Jedikiah.
John, Liz, Stephen and Tyso return to Earth to see if any more Tomorrow People have broken out in their absence. They sense the presence of another telepath, Mike Bell, and decide to leave him to break out in his own time. Unfortunately, his abilities have already attracted the attention of some criminals
Lord Dunning takes Mike's family prisoner in order to force him to use his powers in his service. Meanwhile, John, Liz and Stephen attempt to discover his whereabouts by interrogating Slow and Two Tone.
John, Liz and Stephen are able to secure Mike's release but are unable to prosecute Dunning without revealing the Tomorrow People's existence. However, Mike then goes to Dunning and offers him a partnership.